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OpenTrials
Completed

NCT Number: NCT02158130

Effects of Aerobic Exercise Detraining

The proposed study seeks to better understand the role of body weight, energy expenditure, and energy intake as mechanisms of body weight gain during detraining following aerobic exercise. It is hypothesized that participants in the higher dose exercise group will have greater body weight gain compared to the lower exercise dose and control group from wk 24 to wk 76 follow-up.

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Key information

Conditions

Motor Activity Behavior Body Weight Glucose Metabolism Disorders Hyperinsulinism Insulin Resistance Metabolic Diseases Metabolic Syndrome Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Overweight Pathological Conditions, Signs and Symptoms Sedentary Behavior Signs and Symptoms

Age range

18 year–67 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Pennington Biomedical Research Center

Baton Rouge, Louisiana, 70808, United States

About this study

Eligibility criteria include having successfully completed the main E-Mechanic study, be willing to archive blood samples and not being currently enrolled in another study that may effect body, energy intake or energy expenditure. The investigators will measure body weight, waist/hip circumference, blood pressure, body composition, physical activity, questionnaire about appetite/food intake and physical fitness.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Completed the E-Mechanic study
  • Be willing to archive blood samples
  • Not participating in a study that would alter body weight, energy intake, or energy expenditure.

Treatment and study plan

Primary outcomes

  1. Body Weight

    Time frame: Week 64 - 88 post study randomization

    Fasting body weight

Secondary outcomes

  1. Energy Expenditure

    Time frame: Week 64 - 90 since study randomization

    Energy expenditure is calculated with the Sensewear Armband.

  2. Energy Intake

    Time frame: Week 64 - 90 post study randomization

    Energy expenditure is calculated with the Sensewear Armband and furthermore, energy intake is calculated by adjusting TDEE for change in body weight following the methods used in doubly labeled water adjustment.

Other outcomes

  1. Circumferences

    Time frame: Week 64-88 post study randomization

    Waist and hip circumferences

  2. Blood Pressure

    Time frame: Week 64-88 post study randomization

  3. Body Composition

    Time frame: Week 64 - 88 post study randomization

    Whole Body Scan GE iDXA (Dual energy x-ray absorptiometry)

  4. Triglycerides

    Time frame: Week 64 - 88 post study randomization

  5. Cholesterol

    Time frame: Week 64 - 88 post study randomization

    Total, HDL, and LDL cholesterol

Sponsors and collaborators

Lead sponsor

Pennington Biomedical Research Center

Other

Registry information

Official study title

Effects of Aerobic Exercise Detraining on Energy Balance in Overweight Persons

Acronym: E-Mechanic_Fol

Important dates

Study start
2014
Primary completion
2016
Study completion
2016
First posted
Jun 6, 2014
Registry last updated
Mar 22, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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