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Completed

NCT Number: NCT04589481

Effectiveness of Different Candies Against Bad Breath

This study is to analyze whether the candies can relieve or eliminate bad breath, both subjectively and objectively.

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Key information

Conditions

Bad Breath Halitosis Pathological Conditions, Signs and Symptoms Signs and Symptoms Signs and Symptoms, Digestive

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Universitäres Zentrum für Zahnmedizin UZB

Basel, 4058, Switzerland

About this study

This study is to systematically examine an existing candy, which is easily available and is intended to relieve or eliminate bad breath. The main aim of the study is to determine the effectiveness of the candies on the subjective perception of bad breath. The secondary outcome of the study is to investigate whether there is actually a decrease in volatile sulphur compounds (VSC) in the exhaled air and also a decrease in bad breath during organoleptic measurement.

The purpose of the study is to investigate whether the different candies can relieve or eliminate bad breath, both subjectively and objectively.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Non- smoker
  • No general medical illness or medication

Exclusion criteria

  • Allergies/intolerances to ingredients of the products used
  • Chronic diseases
  • Smoker
  • Pregnancy

Treatment and study plan

Intake of 3 different candies against bad breath

Other

Intake of 3 different candies against bad breath on three different days (2-days interval each) after artificially creating a temporary bad breath (by eating of chips and cheese); analysis of breathing during intake of candy both subjectively and objectively

Primary outcomes

  1. Organoleptic analysis of breathing air sample

    Time frame: max 60 minutes at 3 different days

    Assessment of the patient's bad breath on the basis of the subjective assessment of an investigator (scale of 0 to 5 (0, no odor; 1, questionable odor; 2, slight malodor; 3, moderate malodor; 4, strong malodor; 5, severe malodor))

  2. Measurement of volatile sulphur compounds (VSC) in ppb (parts per billion).

    Time frame: max 60 minutes at 3 different days

    Assessment of the patient's bad breath on the basis of the objective assessment by a sulfide monitor (HaliSens® AI Analytical Innovations GmbH, Moosbach, Germany)

Sponsors and collaborators

Lead sponsor

University Hospital, Basel, Switzerland

Other

Collaborators

  • Ricola Group AG Schweiz

Registry information

Acronym: HALIDROP

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
Oct 19, 2020
Registry last updated
Jun 2, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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