Effectiveness of Dextrose Injection for Osgood-Schlatter Disease

Objective: To examine the potential of dextrose injection versus lidocaine injection versus supervised usual care to change pain/function/activity levels in adolescent athletes with Osgood-Schlatter Disease (OSD).

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Key information

Conditions

Osgood-Schlatter Disease Bone Diseases Enthesopathy Muscular Diseases Musculoskeletal Diseases Osteochondrosis Tendinopathy Tendon Injuries Wounds and Injuries

Age range

9 year–17 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1 / Phase 2

Primary location

Hospital Provincial de Rosario

Rosario, Santa Fe Province, Argentina

About this study

Patients and methods: Girls ages 9-15 years old and boys ages 10-17 years old will be assigned to either therapist-supervised usual care, or to double-blind injection of 1% lidocaine solution with or without 12.5% dextrose. Injections will be administered monthly for three months. All subjects will then be offered dextrose injections monthly as needed. Change in the Nirschl Pain Phase Scale (NPPS) will serve as the primary outcome measure.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age:9-15 year old girls and 10-17 year old boys
Pain Location: Anterior knee.
Sport Type: Jumping or kicking sport.
Team Member with Coach: Member of and organized team with a coach.
Imitation of exact pain and precise location to the tibial tuberosity with a single leg squat.
At least 2 months of formal and gently progressive hamstring stretching, quads strengthening, and gradual sports reintroduction.
Pain with sport at least 3 months.

Exclusion criteria

Patellofemoral crepitus
Patellar origin tenderness

Treatment and study plan

Dextrose Injection

Procedure

12.5 Dextrose in 1% Lidocaine injected monthly for 3 months with a 27 gauge needle on painful areas of the tibial tuberosity, under the patellar tendon.

Lidocaine Injection

Procedure

1% Lidocaine injected monthly for 3 months with a 27 gauge needle on painful areas of the tibial tuberosity, under the patellar tendon.

Usual Care

Other

Therapist supervised exercises that are standard of care for Osgood-Schatter Disease as well as relative rest and gradual resumption of pain-limited sport.

Sponsors and collaborators

Lead sponsor

Universidad Nacional de Rosario

Other

Registry information

Official study title

Phase 2 Study of Dextrose Injection for Sport-Limiting Osgood Schlatter Disease in Adolescents.

Important dates

Study start: 2006
Primary completion: 2009
Study completion: 2010
First posted: Feb 23, 2011
Registry last updated: Feb 23, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed