Effective Dose of Statin Post PCI

In this randomized double-blind clinical trial, the study population was all patients with a recent history of PCI who referred to the professor kojuri cardiovascular clinic for the first post-procedure visit. In the first visit, patients were randomly divided into two groups Both groups were treated with Rosuvastatin 40 mg as high potency statin for one month after PCI. In the first group, after one month, the statin level changed to Rosuvastatin 5 mg daily (moderate intensity). In the second group, 40 mg of Rosuvastatin was continued for one year. Then, the participants were evaluated in terms of MACEs, including any hospitalization due to acute coronary syndrome, as well as history of stroke and myocardial Infarction, subsequent unplanned revascularization and cardiac death. The HS-CRP also checked between two groups

Inclusion criteria

• all patients who have undergone PCI due to chronic stable angina

Exclusion criteria

• Patients with acute coronary syndrome
• Primary LDL>190 mg/DL
• Patients who developed statin-induced myopathy or rhabdomyolysis
• Persistent increase in hepatic enzyme levels or hepatic failure
• Pregnancy and breast feeding
• Statin hypersensitivity
• Patients with history of multiple atherosclerotic events
• Patients who received high intensity statin before the study enrollment.