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Completed

NCT Number: NCT07166029

Effect of Russian Current on Hand Grip Strength and Functional Outcome After Carpal Tunnel Release

this study will be conducted to investigate the effect of Russian current on hand grip strength and functional outcome after carpal tunnel release

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Key information

Conditions

Carpal Tunnel Syndrome Cumulative Trauma Disorders Median Neuropathy Mononeuropathies Nerve Compression Syndromes Nervous System Diseases Neuromuscular Diseases Peripheral Nervous System Diseases Sprains and Strains Wounds and Injuries

Age range

30 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Nawal Sayed

Cairo, Giza Governorate, 11829, Egypt

About this study

Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy syndrome of the upper extremities , the estimated prevalence is 4-5% in the general population ,it occurs due to median nerve compression in carpal tunnel and it is ten times more common in women ,the most common symptoms are numbness and tingling in the radial 3-1/2 finger, night pain, and paresthesias. Although it is most commonly idiopathic, other causes include trauma, oral contraceptive use, pregnancy, arthritis, diabetes hypothyroidism, and repetitive wrist movements. It is well known that distal radius fractures and their sequelae can cause CTS, this suggests that anatomic changes in bony structures of wrist may also contribute to the development of CTS.Russian current (RC), a well-known neuromuscular electrical stimulation operating at 2500 Hz, has demonstrated significant strength improvement over traditional exercises due to its high tolerance and low pain provocation.There are studies about efficacy of Transcutaneous electrical nerve stimulation on wrist pain in patients with CTR but there is lack of literature about efficacy of RC on hand grip strength and function after CTR so this stidu will be conducted.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Fifty-two patients with hand muscles weakness post operative carpal tunnel release ,due to severe carpal tunnel syndrome .
  • Patient's age will range from 30 to 50 years.
  • Patient's body mass index (BMI) will be less than 30kg/m2.
  • Presence of wrist pain associated with hand grip weakness.

Exclusion criteria

  • Patients with any other musculoskeletal or neurological disorders in the hand.
  • Patients with a history of fractures and dislocations in the hand and wrist.
  • Patients with hand deformities and edematous hands.
  • Patients with cervical radiculopathy.
  • Carpal tunnel syndrome due to conditions like hypothyroidism, rheumatoid arthritis, immunosuppression

Treatment and study plan

russian current

Other

russian current will be applied in 50Hz sinusoidal bursts with a duty cycle of 50% (10 s on/10 s off). Russian Stimulation (at 2500Hz or 2.5kHz) has been shown to be effective in increasing muscle strength and torque generation through stimulation of type II muscle fiber. The stimulation will be given for duration of 20 minutes , three tims per week plus selected physical therapy program.

selected physical therapy program

Other

Patients will receive selected physical therapy program

Primary outcomes

  1. hand grip strength

    Time frame: up to four weeks

    hand grip strength will be measured by hand held dynamometer.

  2. hand function

    Time frame: up to four weeks

    hand function will be measured by boston carpal tunnel questionnaire.The Boston Carpal Tunnel Questionnaire (BCTQ) is a patient-reported questionnaire used to assess symptoms and functional limitations in people with carpal tunnel syndrome (CTS). It consists of two modules: an 11-item Symptom Severity Scale (SSS) and an 8-item Functional Status Scale (FSS), which are scored independently on a 1-to-5 Likert scale.A mean score between 1 and 5 is generated for both the SSS and FSS, with higher scores indicating more severe symptoms or greater functional limitation.

Secondary outcomes

  1. wrist range of motion

    Time frame: up to four weeks

    goniometer device will be used to assess wrist range of motion

  2. pain intensity

    Time frame: up to four weeks

    pain will be measured by visual analogue scale. Scores are based on self-reported measures of symptoms that are recorded with a single handwritten mark placed at one point along the length of a 10-cm line that represents a continuum between the two ends of the scale-"no pain" on the left end (0 cm) of the scale and the "worst pain" on the right end of the scale (10 cm).

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Acronym: CTS

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Sep 10, 2025
Registry last updated
May 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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