Effect of Resistant Wheat Starch on Subjective Appetite and Food Intake in Healthy Adults

A randomized, single-blind, cross-over study was conducted to determine the effect of replacing standard wheat flour (SWF) with resistant wheat starch (RWS) on markers of appetite and food intake in healthy adults.

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Key information

Conditions

Feeding Behavior Behavior Behavior, Animal

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

BMI 18.5-29.9 kg/m2
Regular breakfast consumers (>5 days/week)

Exclusion criteria

not weight stable (?3 kg weight change in previous 3 months)
use/used tobacco products
presence of acute or chronic illness
restrained eater (>13 on the restraint section of the three-factor eating questionnaire)

Treatment and study plan

Resistant Starch Type 4

Dietary Supplement

single dose 26g fiber given at the breakfast meal

Other names: Fibersym

Primary outcomes

Caloric intake

Time frame: Single Day

calories consumed at post-treatment lunch meal and total calories consumed on the treatment day

Secondary outcomes

Visual analogue scale measures of subjective appetite

Time frame: Single Day

0-100mm scale to assess hunger, fullness, thirst, desire to eat and prospective consumption
Serum concentrations of biomarkers of appetite

Time frame: 150 minutes

CCK, ghrelin, PYY3-36 and GLP-1
Plasma concentrations of biomarkers of glycemic response

Time frame: 150 minutes

Glucose, Insulin, GLP-1

Sponsors and collaborators

Lead sponsor

Iowa State University

Other

Registry information

Important dates

Study start: 2012
Primary completion: 2013
Study completion: 2014
First posted: Feb 24, 2016
Registry last updated: Feb 24, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed