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Completed

NCT Number: NCT04396262

Effect of Processed Blueberry on Blood Glucose and Antioxidant Status in Human Adults

Canada's Food Guide (2007) recommended 7-10 servings of fruits and vegetables per day for a normal adult population. Although fruit juice (125 ml) is considered as one serving of fruits, the consumption of some fruit juices may be limited due to their high amount of sugar. The consumption of sugary drinks can lead to a rapid rise in postprandial glycaemia. Wild blueberries, due to their high level of anthocyanins, may provide multiple health benefits including improved blood glucose control, however, the consumption of fresh berries is limited by their short seasonal availability. Hydro-Thermodynamic (HTD) processing of blueberries allows the processing of whole berries including their skin and seeds into a beverage with the amount of anthocyanins comparable with fresh berries. The objective of the study is to investigate the effect of HTD-processed blueberries on postprandial glycaemia and antioxidant activity.

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Key information

Conditions

Blood Glucose

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Mount Saint Vincent University

Halifax, Nova Scotia, B3M 2J6, Canada

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy adults
  • Body mass index (BMI) within normal range (18.5-24.9 kg/m2 for adults)

Exclusion criteria

  • Chronic metabolic diseases or inflammatory conditions
  • Smokers
  • A medication that influences glucose control or gastrointestinal function
  • Known allergies
  • Intellectual disabilities

Treatment and study plan

Food-1

Other

HTD-blueberry beverage with white bread.

Food-2

Other

Sweetened water with white bread as a control.

Primary outcomes

  1. Blood glucose

    Time frame: 0-120 min

    The concentration of glucose in venous blood after consuming HTD-blueberry beverage with white bread or water control with white bread.

Secondary outcomes

  1. Postprandial antioxidant activity in blood

    Time frame: 0-120 min

    The total antioxidant activity in blood plasma determined using a commercial Antioxidant Assay Kit.

Sponsors and collaborators

Lead sponsor

Mount Saint Vincent University

Other

Registry information

Official study title

Effect of Hydro-Thermodynamic (HTD) Processed Blueberries on Postprandial Blood Glucose Control and Antioxidant Status in Human Adults

Important dates

Study start
2015
Primary completion
2016
Study completion
2022
First posted
May 20, 2020
Registry last updated
Mar 20, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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