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Completed

NCT Number: NCT03530280

Effect of Pregabalin or Adductor Canal Block on Postoperative Analgesia

arthroscopically Anterior Cruciate Ligament Reconstruction (ACL) under spinal anesthesia were included in this study.

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Key information

Conditions

Postoperative Pain After Knee Arthroscopy Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Complications Signs and Symptoms

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Diskapi Teaching and Research Hospital

Ankara, Altindag, Turkey (Türkiye)

About this study

Patients who American Society of Anesthesiologists (ASA) classification I to II scheduled to undergo arthroscopically assisted ACL reconstructions under spinal anesthesia are included in this study. The first group is administered 150 mg oral pregabalin 1 hour before surgery and the postoperative sham block was performed with an ultrasound probe. The second group is the control group; patients in this group are administered a placebo capsule 1 hour before surgery and sham block was performed with an ultrasound probe.The third group is administered a placebo capsule 1 hour before surgery and postoperative adductor canal block is performed. All patients will be received postoperative a tramadol i.v. patient control analgesia device. At the end of 24 hours, the total amount of tramadol consumed by the patient will be recorded from the patient control analgesia. NRS score, white fast track, satisfaction will be questioned.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients between the ages of 18 and 70 years
  • American Society of Anesthesiologists I or II
  • Scheduled to undergo knee arthroscopy

Exclusion criteria

  • allergic to any medicines
  • History of drug or alcohol abuse,
  • Opioids or sedative medications
  • History of psychiatric conditions
  • Pregnant or lactating women

Treatment and study plan

pregabalin (Lyrica)

Drug

preoperative pregabalin and the postoperative sham block will perform.

Placebo oral tablet

Drug

The preoperative placebo oral tablet and the postoperative sham block will perform.

adductor canal block including bupivacaine

Drug

The preoperative placebo oral tablet and adductor channel block including 10 mL of 0.25% bupivacaine with 5 μg/mL epinephrine

Primary outcomes

  1. 11-point numerical rating scale (NRS)

    Time frame: 24 hours

    11-point numerical rating scale for pain (0='no pain' and 10='worst pain possible pain') were explained.

  2. tramadol consumption

    Time frame: 24 hours

    24 hours tramadol consumption will be recorded as milligrams

Sponsors and collaborators

Lead sponsor

Ankara Diskapi Training and Research Hospital

Other

Registry information

Official study title

Effect of Pregabalin or Adductor Canal Block on Postoperative Analgesia After Arthroscopic Anterior Cruciate Ligament Reconstruction (ACL)

Important dates

Study start
2018
Primary completion
2018
Study completion
2018
First posted
May 21, 2018
Registry last updated
Oct 18, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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