Effect of Passive Smoking on Oxidative Stress and Dental Caries in Children

The purpose of the present study was to determine the effect of passive smoking on oxidative stress and dental caries in children.A total of 180 children were included to the study as follows; 90 children exposed to passive smoking, and 90 children in the control group (unexposed controls). Also demographic data were recorded (age, gender, parental education levels, child's tooth-brushing habit and child's daily dietary sugar exposure, family income). Dental examination of children were performed and caries prevalence of the patients were recorded. Unstimulated saliva samples were collected from children. Saliva 'cotinine levels' and oxidative stress markers 'total antioxidant status' (TAS), and' total oxidant status' (TOS) were evaluated by using Enzyme-linked immunosorbent assay (ELISA). The obtained data parameters of the two groups were evaluated and comparison was performed.

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Key information

Conditions

Oxidative Stress Dental Caries Passive Smoking Stomatognathic Diseases Tooth Demineralization Tooth Diseases

Age range

6 year–12 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

-Systemically healthy children

Exclusion criteria

Uncooperative children
The presence of orthodontic/intraoral appliance
Any disease or condition known to affect oxidative stress

Treatment and study plan

taking saliva samples to determine oxidative stress markers TAS and TOS

Diagnostic Test

Primary outcomes

determining oxidative stress marker in saliva: TAS

Time frame: 1 day (once after the dental examination)]

Unstimulated saliva samples were collected from children.
determining oxidative stress marker in saliva: TOS

Time frame: 1 day (once after the dental examination)

Unstimulated saliva samples were collected from children.
determining caries prevalence

Time frame: 1 day (once for dental examination)

Children were examined to determine caries prevalence.

Sponsors and collaborators

Lead sponsor

Merve Erkmen Almaz

Other

Collaborators

Kırıkkale University

Registry information

Important dates

Study start: 2016
Primary completion: 2018
Study completion: 2018
First posted: Mar 6, 2020
Registry last updated: Mar 9, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed