Effect of Pain Control on the Diagnosis of Acute Appendicitis on the Diagnostic Accuracy of General Surgeon

The pain control in surgical abdomen has been in debate in masking the correct diagnosis. We would like to investigate the effect of pain control on the diagnostic accuracy of surgeon in suspicious appendicitis patients.

We would give morphine or placebo to the patients suspected of appendicitis randomly and in double-blinded manner, and then surgeons would exam the patient and give the impression for the possibility of the appendicitis(grading 1 to 4).

With this grading, we compare these impression between two groups.

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Key information

Conditions

Appendicitis Cecal Diseases Digestive System Diseases Disease Gastroenteritis Gastrointestinal Diseases Infections Intestinal Diseases Intraabdominal Infections Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

16 year–90 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Seoul National University Bundang Hospital, Emergency room

Seongnam-si, Gyeonggi-do, 463-707, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

the patients suspected of acute appendicitis over 15 years

Exclusion criteria

less than 15 years
pregnant
allergic to morphine
systolic blood pressure<100mmHg
received pain killer prior to ED visit
do not consent

Treatment and study plan

Morphine

Drug

Primary outcomes

AUC of ROC of the impression of diagnosis for the appendicitis by surgeon

Sponsors and collaborators

Lead sponsor

Seoul National University Hospital

Other

Registry information

Important dates

Study start: 2008
Primary completion: 2011
Study completion: 2011
First posted: Oct 31, 2008
Registry last updated: Jul 26, 2011

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed