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Completed

NCT Number: NCT04448275

Effect of Neurodynamics Nerve Flossing on Femoral Neuropathy in Haemophilic Patients

To investigate the effect of Neurodynamics Nerve flossing on femoral neuropathy in patients with haemophilia

Background: heamophilia is one of the serious chronic disorders in children and adolescents which results in less physical activities and restlessness hours than their peer.

HYPOTHESES:

This study will hypnotize that:

Neurodynamics Nerve flossing will have a significant effect on femoral neuropathy in patients with haemophilia

RESEARCH QUESTION:

will the Neurodynamics Nerve flossing has an effect on femoral neuropathy in patients with haemophilia?

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Key information

Conditions

Femoral Neuropathy in Haemophilic Patients Blood Coagulation Disorders Blood Coagulation Disorders, Inherited Coagulation Protein Disorders Congenital, Hereditary, and Neonatal Diseases and Abnormalities Femoral Neuropathy Genetic Diseases, Inborn Hematologic Diseases Hemic and Lymphatic Diseases Hemophilia A Hemorrhagic Disorders Mononeuropathies Nervous System Diseases Neuromuscular Diseases Peripheral Nervous System Diseases

Age range

12 year–16 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

October 6 University

Giza, El-Sheikh Zayed City Giza 1133 Egypt, Egypt

About this study

Haemophilic patients with Femoral Neuropathy will be randomly divided in two equal groups control group which will receive conventional selected exercise program and study group will receive the same exercise training program in addition to Neurodynamics Nerve flossing three times per week for three successive months.

The Evaluation will done pre and post interventions included:

femoral nerve motor conduction velocity, muscle test For Iliopsoas and Quadriceps muscles and Pain visual analogue scale.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • hemophilia A or B, all the patients
  • positive femoral nerve tension test
  • the Manual muscle test for iliopsoas and quadriceps muscles in all patients not less than grade 2 according to the oxford scale
  • the age ranging from (12:16) years
  • all the participants will be able to communicate verbally ,obey commands and instructions and co-operate with testing and training protocols

Exclusion criteria

  • any participants have auditory, visual and sever cardiac disorders
  • Patients who have mild degree of hemophilia
  • Patients who have joint, muscle bleeding or pain in the lower limb in the preceding 3 weeks
  • patients with any other neurological disorders or musculoskeletal disorders or deformities of the lower limb.

Treatment and study plan

Neurodynamics Nerve flossing

Other

Neurodynamics Nerve flossing for femoral nerve that includes two techniques inform of:

"slider technique" and the second is the "tensioner technique

conventional selected exercise program

Other

Ultrasound therapy The flexibility exercises for iliopsoas & quadriceps The iliopsoas & quadriceps muscles strength exercise

Primary outcomes

  1. Electromyography Nerve conduction study

    Time frame: 12 weeks

    Femoral Nerve motor conduction velocity (m/sec.) , via the Neuropack S1 MEB9004 EMG device

  2. Femoral Nerve Tension Test, for femoral nerve injury

    Time frame: 12 weeks

    Femoral Nerve Tension Test is a neural tension test used to stress the femoral nerve

    A positive test was be reproduction of the patient's symptoms as burning discomfort in the groin or anterior thigh occurred if there was femoral nerve involvement.

  3. Manual muscle test, Oxford five grades of muscle power assessment

    Time frame: 12 weeks

    The group Manual muscle test was used for testing the strength of iliopsoas and quadriceps muscles, according to the Oxford Scale as the Muscle strength is often rated on a scale of 0/5 as follow:

    (0/5) no contraction of muscle, (1/5) muscle flicker contraction, but no movement (2/5) movement possible, but not against gravity (test the joint in its horizontal plane), (3/5) movement possible against gravity, but not against resistance by the therapist, (4/5) movement possible against some resistance by the examiner and (5/5) normal strength

Sponsors and collaborators

Lead sponsor

Lama Saad El-Din Mahmoud

Other

Registry information

Important dates

Study start
2020
Primary completion
2020
Study completion
2020
First posted
Jun 25, 2020
Registry last updated
Jan 6, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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