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Completed

NCT Number: NCT01952977

Effect of Medium Chain Triglyceride Consumption on Appetite

The purpose of this study is to test the effects of medium chain triglyceride consumption, relative to long chain triglycerides, on hormones involved in appetite regulation and food intake in overweight men. We expect medium chain triglycerides to reduce appetite and food intake and to do so by increasing levels of hormones known to be involved in satiety and reduce levels of those involved in appetite.

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Key information

Conditions

Obesity Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

19 year–50 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

New York Obesity Nutrition Research Center

New York, 10025, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Males
  • Weight stable (<10 lb over previous 3 months)
  • Overweight (body mass index 25-29.9)

Exclusion criteria

  • Smokers
  • Excessive caffeine users
  • Severe health conditions
  • Allergy to food products/ingredients in the study
  • Taking medications known to affect energy expenditure or gastrointestinal function

Treatment and study plan

Test breakfast

Dietary Supplement

Primary outcomes

  1. Food intake

    Time frame: up to 3 hours

    Intake at an ad libitum meal 3 h after test oil consumption (Study 1) or 1 h after a pre-load containing the test oil (Study 2)

Secondary outcomes

  1. Ghrelin

    Time frame: 3 hours

  2. Peptide YY

    Time frame: 3 hours

  3. Glucagon-like peptide 1

    Time frame: 3 hours

  4. Insulin

    Time frame: 3 hours

  5. Triglycerides

    Time frame: 3 hours

  6. Leptin

    Time frame: 3 hours

Sponsors and collaborators

Lead sponsor

St. Luke's-Roosevelt Hospital Center

Other

Registry information

Acronym: MCT

Important dates

Study start
2010
Primary completion
2011
Study completion
2011
First posted
Sep 30, 2013
Registry last updated
Sep 30, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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