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Completed

NCT Number: NCT02405494

Effect of Liquid Volume and the Amount of Incorporated Gas Into a Carbohydrate/Protein Beverage on Satiety

Liquid foams can be formed by trapping pockets of gas in a beverage. The primary objective of this study is to test the individual contribution, and possible interaction, of the liquid volume and gas to liquid volume ratio (i.e. %overrun (%OR, defined as 100 x [gas volume/liquid volume]) of a beverage to its satiating properties.

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Key information

Conditions

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Leatherhead Food Research

Leatherhead, Surrey, United Kingdom

About this study

It is not known how the liquid and gas volumes of a liquid foam contribute to its satiating properties and how and if these factors interact. The best way to assess these parameter combinations and their interactions is to use a special statistical approach named "Response Surface Methodology" (RSM). The current study therefore has a Central Composite Design with 9 foams differing in liquid volume and in ratio of gas to liquid volume (%overrun, which is defined as 100 x gas volume/liquid volume).

Each subject will be appointed to a single parameter combination and receives this parameter combination twice, separated by a one-week wash-out period.

On both test days subjects' self-assessment of feelings of satiety and physical discomfort will be recorded during 4 hours post-consumption of the treatment using Electronic Visual Analogue Scale.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • BMI between 21 and 32 kg/m²
  • Apparently healthy: measured by questionnaire: no reported current or previous metabolic diseases or chronic gastrointestinal disorders
  • Reported dietary habits: no medically prescribed diet, no slimming diet, used to eat 3 meals a day, no vegetarian.
  • Reported intense sporting activities below 10h/w
  • Reported alcohol consumption below 14 units/w (female volunteers) or below 21 units/w (male volunteers)

Exclusion criteria

  • Dislike, allergy or intolerance to test products or indicating to be unable to consume 514 ml of aerated test product
  • Any food allergy, or dislike or intolerance with the foods supplied during the study
  • Eating disorder (measured by SCOFF questionnaire, 2 or more"yes" responses) High or very high restrained eaters (measured by questionnaire; score of 15 or higher, Polivy et al. 1978)
  • Reported medical treatment that may affect eating habits/satiety
  • Reported lactating (or lactating < 6 weeks ago), pregnant (or pregnant < 6 months ago) or wish to become pregnant during the study

Treatment and study plan

Beverage 1

Dietary Supplement

Beverage 2

Dietary Supplement

Beverage 3

Dietary Supplement

Beverage 4

Dietary Supplement

Beverage 5

Dietary Supplement

Beverage 6

Dietary Supplement

Beverage 7

Dietary Supplement

Beverage 8

Dietary Supplement

Beverage 9

Dietary Supplement

Primary outcomes

  1. Hunger and satiety questions (Area under the time curve of hunger and satiety scores (as rated by the subjects on a Visual Analog Scale)

    Time frame: 245 minutes

    Area under the time curve of hunger and satiety scores (as rated by the subjects on a Visual Analog Scale)

Sponsors and collaborators

Lead sponsor

Unilever R&D

Industry

Registry information

Official study title

Effect of Liquid Volume and the Amount of Incorporated Gas Into a Carbohydrate/Protein Beverage on Satiety: a Response-surface-model Study

Important dates

Study start
2011
Primary completion
2011
Study completion
2011
First posted
Apr 1, 2015
Registry last updated
Apr 10, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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