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Completed

NCT Number: NCT00645775

Effect of Irvingia Gabonensis (Bush Mango)on Parameters Associated With Metabolic Syndrome

The study investigated the use and efficacy of the seeds of African bush mango (Irvingia gabonensis)to control body weight, blood lipids and hormones in overweight and obese people.

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Key information

Conditions

Metabolic Syndrome Body Weight Body Weight Changes Dyslipidemia Dyslipidemias Glucose Metabolism Disorders Hyperinsulinism Insulin Resistance Lipid Metabolism Disorders Metabolic Diseases Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms Weight Loss

Age range

19 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Laboratory of Nutrition & Nutritional Biochemistry

Yaoundé, Centre Region, BP812, Cameroon

About this study

To assess the effects of seeds of Irvingia gabonensis on body weight, fasting blood glucose, plasma total and LDL cholesterol in 102 overweight and obese participants.

The study was a 10 week randomized, double blind, placebo controlled design. participants were randomly divided into 2 groups of 51 participants each. Group 1 was the placebo group, while Group 2 was the active group. Each group received 2 daily doses of 125 mg (before meals) of either placebo or Irvingia gabonensis.

Weight as well as fasting blood was taken at baseline and at 4, 8 and 10 weeks. No major detary changes or exercises were suggested during the study period.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • BMI>26

Exclusion criteria

  • Diabetics Pregnant and lactating Participating in any other weight reducing program Smokers

Treatment and study plan

IGOB131

Dietary Supplement

Comparison of 250 mg per day of Irvingia gabonensis to placebo

Primary outcomes

  1. Weight change

    Time frame: 10 weeks

Secondary outcomes

  1. Change in blood lipids and hormone levels

    Time frame: 10 weeks

Sponsors and collaborators

Lead sponsor

Gateway Health Alliance

Industry

Collaborators

  • University of Yaounde

Registry information

Official study title

The Efficacy of Irvingia Gabonensis (Bush Mango) in the Management of Overweight, Obesity and Metabolic Syndrome in Cameroon.

Important dates

Study start
2006
Primary completion
2007
Study completion
2007
First posted
Mar 28, 2008
Registry last updated
Mar 28, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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