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Completed

NCT Number: NCT03332641

Effect of Intake of Citron(Citrus Junos Siebold ex Tanaka) Peel Extract on Blood Cholesterol.

This study was conducted to investigate the effects of daily supplementation of Citron(Citrus Junos Siebold ex Tanaka) Peel Extract on improvement of Blood Cholesterol.

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Key information

Conditions

Hyperlipidemia Dyslipidemias Hyperlipidemias Lipid Metabolism Disorders Metabolic Diseases Nutritional and Metabolic Diseases

Age range

19 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hanyang University

Seoul, 04763, South Korea

About this study

This study was a 12 weeks, randomized, double-blind, placebo-controlled human trial. Twenty subjects were randomly divided into Citron(Citrus Junos Siebold ex Tanaka) Peel Extract or a placebo group. Blood cholesterol profiles before and after the intervention.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 19-75 years with Total cholesterol 200-239 mg/dL

Exclusion criteria

  • Lipid lowering agent within past 6 months
  • Severe cardiovascular disease(Mvodardial infarction, stroke, etc)
  • Renal disease(Heredity hyperlipidemia, Acute/Chronic renal failure, Nephrotic syndrome, ect)
  • Cancer, Respiratory organ disease(Asthma, Chronic obstructive pulmonary disease)
  • Diabetes mellitus
  • Allergic or hypersensitive to any of the ingredients in the test products
  • History of disease that could interfere with the test products or impede their absorption
  • Under antipsychotic drugs therapy within past 2 months
  • History of alcohol or substance abuse
  • Participation in any other clinical trials within past 2 months
  • Laboratory test by show the following results
  • Pregnancy or breast feeding
  • Not Contraception(except: Surgery for female infertility)

Treatment and study plan

Citron peel extract

Dietary Supplement

Citron peel extract for 12 weeks

Placebo

Dietary Supplement

Placebo for 12 weeks

Primary outcomes

  1. Changes of Cholesterol

    Time frame: 12 weeks

    Changes of Cholesterol were assessed before and after the intervention

Secondary outcomes

  1. Changes of Lipid profile

    Time frame: 12 weeks

    Changes of Lipid profile were assessed before and after the intervention

  2. Changes of Oxidized LDL

    Time frame: 12 weeks

    Changes of Oxidized LDL were assessed before and after the intervention

Sponsors and collaborators

Lead sponsor

Hanyang University

Other

Registry information

Official study title

A 12-week, Randomized, Double-blind, Placebo-controlled Human Trial to Evaluate the Efficacy and Safety of Citron(Citrus Junos Siebold ex Tanaka) Peel Extract on Improvement of Blood Cholesterol

Important dates

Study start
2017
Primary completion
2017
Study completion
2017
First posted
Nov 6, 2017
Registry last updated
Nov 17, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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