Glycemic Index Laboratories, Inc.
Toronto, Ontario, M5C 2X3, Canada
NCT Number: NCT03224806
Health organizations recommend fiber-rich and whole-grain foods for healthy diets due to their physiological beneficial effects on human health. But, little information is available between these 2 food categories, i.e. fiber added to foods versus fiber naturally present in foods. The present study investigated the effect of enriching white wheat flour with wheat bran at 2 levels (15 and 30%) to produce 15% fiber-rich bread (15FRB) and 30% fiber-rich bread (30FRB) and compared them with white bread (WB) and whole-grain bread (WGB) in terms of bread quality, palatability, satiety, and glycemic response. Ten healthy subjects were studied on 4 separate days with each subject testing all 4 types of bread. On each test day subjects came to the test center after an overnight fast. After 2 fasting finger-prick blood samples, they ate a portion of one of the breads containing 50g available carbohydrate and had further blood samples at intervals over 2 hours. They also rated their feelings of satiety fasting and at intervals over 2 hours.
Looking for future studies?
Notify Me18 year–75 year
All sexes
Interventional
Not applicable
Toronto, Ontario, M5C 2X3, Canada
Health organizations recommend fiber-rich and whole-grain foods for healthy diets due to their physiological beneficial effects on human health. But, little information is available between these 2 food categories, i.e. fiber added to foods versus fiber naturally present in foods. The present study investigated the effect of enriching white wheat flour with wheat bran at 2 levels (15 and 30%) to produce 15% fiber-rich bread (15FRB) and 30% fiber-rich bread (30FRB) and compared them with white bread (WB) and whole-grain bread (WGB) in terms of bread quality, palatability, satiety, and glycemic response. Ten healthy subjects were studied on 4 separate days with each subject testing all 4 types of bread. On each test day subjects came to the test center after an overnight fast. After 2 fasting finger-prick blood samples 5 minutes apart, they ate a portion of one of the breads containing 50g available carbohydrate and had further blood samples at 15, 30, 45, 60,90 and 120 min after starting to eat. After each blood sample also rated their feelings of satiety on a 7-point scale from extremely hungry to extremely full.
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
156.8g wholegrain bread
122.6g white bread
139.2g bread made with 15% added wheat bran
166.5g bread made with 30% added wheat bran
Time frame: 2 hours
Incremental area under the glucose response curve ignoring area below fasting glucose
Time frame: 2 hours
Incremental area under the satiety response curve
Time frame: 2 hours
Incremental area under the hydrolysis curve (amount of glucose released during in-vitro digestion of the breads) expressed as a percentage of that for white bread.
Glycemic Index Laboratories, Inc
Industry
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT07243743
Glycemic Response
Toronto, Ontario, Canada
View Trial DetailsNCT07175740
Behavior, Diabetes Mellitus
Québec, Quebec, Canada
View Trial DetailsNCT06797349
Glycemic Response
Toronto, Ontario, Canada
View Trial DetailsNCT06048978
Glycemic Response
Toronto, Ontario, Canada
View Trial Details