Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07231887

Effect of Different Positions During Extubation on Incidence of Hypoxemia in the Peri Extubation Period

Pediatric Obstructive Sleep Apnea Syndrome (OSAS) is common, often due to enlarged tonsils/adenoids. Tonsillectomy/adenoidectomy frequently performed under GA with tracheal intubation due to the age of children. Risk of hypoxemia and respiratory complications during the peri-extubation period is high.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Age range

2 year–10 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

The most common disorder of sleep apnea in children is obstructive sleep apnea syndrome (OSAS), characterized by interrupted breathing and partial or complete obstruction of the upper airway, the main factor is the enlargement of the tonsils and adenoids in the pediatric pharynx. The clinical symptoms are snoring, and open-mouth breathing, then resulting in hypoventilation and hypoxemia. Due to the age of children, tonsillectomy and adenoidectomy are often performed under general anesthesia with tracheal intubation. The risk of hypoxemia and the degree of oxygen saturation reduction are bigger when the mask was removed in the supine position, and the most serious complication also occurred in the supine position. Therefore, the lateral position is preferable to the supine position for mask removal. There are few reports on the effect of different positions on complications related to tracheal extubation after tonsillectomy and adenoidectomy under general anesthesia in children with OSAS. In this study, we will investigate and compare whether the use of lateral position or semi-prone position impact on the occurrence of choking, agitation, decreased pulse oxygen saturation - (SpO2) and the oral and nasal secretions during the awakening period.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 2-10 years
  • American Society of Anesthesiologists physical status classification (ASA) I - II
  • Patients scheduled for ENT procedures involving tonsillectomy, adenoidectomy or adenotonsillectomy

Exclusion criteria

  • • Patient legal guardian refusal to participate in the study.
  • Children with cardio-pulmonary disease

Treatment and study plan

positioning during peri-extubation

Procedure

investigate and compare whether the use of lateral position or semi-prone position impact on the occurrence of choking, agitation, decreased pulse oxygen saturation - (SpO2) and the oral and nasal secretions during the awakening period.

Primary outcomes

  1. Incidence of hypoxemic events in the peri-extubation period

    Time frame: one hour after extubation

    Hypoxemic events which last > 2 seconds after extubation will be recorded when Spo2 is less than 94% on room air.

Secondary outcomes

  1. Incidence of respiratory complications

    Time frame: one hour after extubation

    Incidence of respiratory complications such as choking, laryngospasm, posterior tongue drop.

Study contacts

Contact information is provided by the study sponsor or research team.

Mohammed R. Mahmoud

CONTACT

[email protected]

01120792510‬‬‬‬‬‬ ext. 002

Shimaa A. Abbas

CONTACT

[email protected]

01002953253 ext. 002

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Effect of Different Positions During Extubation on Incidence of Hypoxemia in the Peri Extubation Period of Pediatric OSAS Surgery Under General Anesthesia, Randomized Controlled Trial

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Nov 17, 2025
Registry last updated
Nov 19, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.