Effect of Cinnamon on Glucose and Lipid Levels in Non-Insulin Dependent Type 2 Diabetes Mellitus

The purpose of this study is to determine the effects of cinnamon on serum glucose and lipid levels in people with non-insulin dependent type 2 diabetes mellitus.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Diabetes Mellitus, Adult Onset Diabetes Mellitus Diabetes Mellitus, Type 2 Dyslipidemias Endocrine System Diseases Glucose Metabolism Disorders Hyperinsulinism Hyperlipidemias Insulin Resistance Lipid Metabolism Disorders Metabolic Diseases Nutritional and Metabolic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

General Clinical Research Center

Oklahoma City, Oklahoma, 73117, United States

About this study

Forty people with non-insulin dependent type 2 diabetes mellitus will be randomized to receive either cinnamon or placebo for three months. The dose of cinnamon will be one gram daily. Fasting serum glucose, triglyceride, total cholesterol, LDL, HDL, and insulin levels will be measured at baseline and at 1, 2, and 3 months. HbA1c levels will be measured at baseline and at 3 months. Patients will be monitored for compliance, adverse effects, and dietary changes.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Type 2 diabetes mellitus
HbA1C > 6.0%
Age 18 and above
Able to obtain consent

Exclusion criteria

Currently taking insulin
Pregnancy
End-stage renal disease
Hemolytic anemia
Cinnamon intolerance
Inability or unwillingness to adhere to study protocol

Treatment and study plan

Cinnamon or placebo 500 mg capsule twice daily

Drug

Cinnamon 500 mg capsule twice daily or placebo capsule twice daily

Primary outcomes

- Primary outcomes include HbA1c, glucose, total cholesterol, LDL cholesterol, HDL cholesterol, and triglycerides levels.

Time frame: 3 months

Sponsors and collaborators

Lead sponsor

University of Oklahoma

Other

Collaborators

National Center for Research Resources (NCRR)

Registry information

Important dates

Study start: 2005
Primary completion: 2007
Study completion: 2007
First posted: Oct 12, 2005
Registry last updated: Sep 22, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed