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Completed

NCT Number: NCT07034001

Effect of Anesthesia on Frontal QRS t Angle in Obese Individuals

The aim of this observational study is to determine the effect of anesthesia on frontal qrs-t angle changes in obese individuals. To learn the long-term effects of intervention A in individuals with a body mass index > 30 who received intervention A. The main question it aims to answer is:

Does frontal qrs-t angle change occur in obese individuals due to anesthesia? Preoperative and intraoperative ECG changes of individuals undergoing surgery will be examined.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Amasya University

Amasya, Turkey (Türkiye)

About this study

All patients were routinely administered 500 cc of Ringer's lactated solution intravenously (IV) before anesthesia and taken to the operating room. The body mass index will be calculated according to the formula body weight kg / height cm2. Obese patients with a BMI above 30 kg/m2 were recorded as group 2, and non-obese patients with a BMI below <30 kg/m2 were recorded as group 1. Patients were taken to the operating room and routine ECG, noninvasive blood pressure, pulse, and oxygen saturation monitoring (CARESCAPE™ B650, GE Healthcare, USA) was performed. All patients were hydrated intravenously (IV) with 500 cc of Ringer's lactated solution after a 6-hour fast. For premedication, midazolam 1 mg IV and pantoprazole 40 mg IV were administered. For anesthesia induction, propofol 2 mg/kg, fentanyl 2 mg/kg and rocuronium 0.6 mg/kg were administered intravenously.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • People between the ages of 18-65 who underwent laparoscopic cholecystectomy surgery

Exclusion criteria

  • known coronary artery disease, atrial fibrillation, heart failure, liver failure, kidney failure, preexcitation syndromes, electrolyte disorders, use of drugs that prolong the QT interval, respiratory failure and metabolic diseases were excluded from the study

Treatment and study plan

Primary outcomes

  1. EKG

    Time frame: 1 day

    Frontal qrs t angle and qt interval examination on ecg

  2. Frontal qrs-t angle

    Time frame: 1 day

    Frontal qrs t angle examination on ecg

Sponsors and collaborators

Lead sponsor

Amasya University

Other

Registry information

Official study title

Effect of Anesthesia on Frontal QRS-T Angle in Obese Individuals

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Jun 24, 2025
Registry last updated
Jun 24, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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