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OpenTrials
Completed

NCT Number: NCT05202535

Effect of Aerobic Exercise Training in Obese Adults

To determine the effect of aerobic exercise training on arterial stiffness and hemodynamics in obese adults. Proper evidence on the effect of aerobic exercise training on both arterial stiffness and hemodynamics are sparsely present in obese adults whereas separate studies were done in mainly hypertensive and cardiovascular disease populations.

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Key information

Conditions

Obesity Body Weight Nutrition Disorders Nutritional and Metabolic Diseases Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

20 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Polyclinic Hospital

Islamabad, Punjab Province, 04404, Pakistan

About this study

Obese adults always have been trying to improve their quality of life by managing the complications associated with obesity like arterial stiffness and disturbed hemodynamics.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Body mass index ≥28 kg/m²
  • Able to do exercise

Exclusion criteria

  • Involved in structured physical activity in last 6 months
  • History of chronic systemic disease (cardiovascular, pulmonary, and metabolic disease)
  • Continuous medication use.
  • MSK or Neurological problems
  • Pregnant females

Treatment and study plan

Aerobic exercise training

Other

Hospital-based aerobic exercise training for 15-30 minutes including pre and post-vitals assessment.

3x/week on alternate days for 8 weeks at 40-70% of HR Max

Conventional Therapy

Other

Patient education and counseling with diet plan.Walking 3 days15min/day for 8 weeks

Primary outcomes

  1. Arterial Stiffness

    Time frame: 6 weeks

    Gradual fragmentation and loss of elastin fibers and accumulation of stiffer collagen fibers in the arterial wall. Calculated through Arterial stiffness index.

  2. Hemodynamics

    Time frame: 6 weeks

    Factors that govern blood flow calculated through Rate Pressure Product.

Sponsors and collaborators

Lead sponsor

Riphah International University

Other

Registry information

Official study title

Effect of Aerobic Exercise Training on Arterial Stiffness and Hemodynamics in Obese Adults.

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Jan 21, 2022
Registry last updated
Sep 16, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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