Effect of 4-week Oral Administration of a Fermented Dairy Product Containing Lactobacillus Rhamnosus CNCM I-3690, on Subjective State Anxiety Levels in Healthy Women Undergoing Academic Stress.

Inclusion criteria

• SI01: Free-living Participant who fully understands and agree to the objectives of the study, who gave signed and dated informed consent
• SI02: Women of 20 to 30 years of age inclusive
• SI03: Participants who are healthy as determined by medical evaluation including medical and surgical history and full physical examination.
• SI04: Body mass index (BMI) within the range 18 and 30 kg/m2 (bounds included).
• SI05: Woman participants.
• SI06: Student defending a bachelor's or master's thesis in front of a jury
• SI07: Subject who regularly consumes dairy fermented products containing live bacteria and willing to consume 2 units of investigational product per day during the study.
• SI08: Subject willing to strictly follow instructions on diet, medication and substance use for the entire duration of the study.

Exclusion criteria

• SE01: subject with chronic gastrointestinal disorders or symptoms, with celiac disease, diagnosed type 1 or type 2 diabetes mellitus, with psychiatric disease including but not limited to depression and general anxiety disorder
• SE03: subject with food allergy, history of atopic conditions (eczema, allergic asthma, allergic rhino conjunctivitis) requiring active treatment, with first degree relatives with coeliac disease, inflammatory bowel disease (IBD) or type 1 diabetes, with known or suspected lactose intolerance
• SE4: Subject with eating disorders, chronic or iatrogenic immunodeficiency (e.g. Chemotherapy, HIV), presenting a severe evolutive or chronic pathology (e.g. cancer, tuberculosis, Crohn's disease, cirrhosis, multiple sclerosis)
• SE5: Subject with cardiac, respiratory (including asthma) or renal insufficiency, cardiomyopathy, valvulopathy and medical history of rheumatic fever and/or with a positive test for COVID-19 infection or presenting any symptoms of COVID infection in the past 2 weeks
• SE6: Subject receiving systemic treatment or topical treatment likely to interfere with evaluation of the study parameters (antibiotics, intestinal or respiratory antiseptics, anti-rheumatics, and steroids prescribed in chronic inflammatory diseases, antiphlogistic, anti-inflammatory and PPIs)
• SE7: Subject who has planned to participate in another investigational study OR subject involved in any other clinical study within the preceding month
• SE8: Subjects planning to significantly change their diet during the period of the study or who have changed his/her dietary habits within the 4 weeks preceding the study (e.g. start of a diet high in fibres)
• SE9: Pregnant woman or woman planning to become pregnant during the study; breast-feeding woman.