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NCT Number: NCT03534726

Edema and Fibrosis CMR Imaging in Cardiomyopathy

7 Tesla MRI is a new magnetic field strength that has become available at Penn for cardiovascular MRI. This new scanner has potential to improve assessment of cardiovascular disease due to its increased signal-to-noise ratio, higher spatial resolution, and response to magnetic properties of tissue at high field. The purpose of this study is to assess the feasibility of 7 T CMR. Secondly, we wish to investigate its use, to improve clinical and research MRI. Altogether, 7 T may permit better clinical diagnosis of cardiomyopathy.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Cardiomyopathies Cardiovascular Diseases Heart Diseases

Age range

20 year–70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Subjects between the ages of 20-70 years old

Exclusion criteria

  • Advanced renal disease (estimated GFR rate < 30 mL/min) or hypersensitivity to gadolinium contrast agent.
  • Presence of cardiac pacemaker or implanted cardioverter defibrillator
  • Pregnancy
  • Inability to provide informed consent
  • Other contraindications to MRI (such as claustrophobia)

Treatment and study plan

7 T CMR

Device

7 tesla MRI device

Primary outcomes

  1. ejection fraction

    Time frame: 5 years

Sponsors and collaborators

Lead sponsor

University of Pennsylvania

Other

Registry information

Official study title

Edema and Fibrosis Cardiac Magnetic Resonance Imaging in Cardiomyopathy

Important dates

Study start
2018
Primary completion
2026
Study completion
2027
First posted
May 23, 2018
Registry last updated
Feb 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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