Eating Behavior in Adolescents

This study will explore the eating habits of adolescents and determine if eating behavior is linked to genetics.

Healthy adolescents between 13 and 17 years of age may be eligible for this study. Candidates come to the NIH Clinical Center at 8:00 AM to be screened with the following:

* Medical history and brief physical examination, including height, weight, and body fat measurements. Body fat is measured using a device called a Bod Pod. The adolescent sits inside the device for about 5 minutes and the machine determines body fat by measuring air movement. The adolescent must wear a tight-fitting swimsuit for this test. * Urine test to look for sugar or protein in the urine and to test for pregnancy in females. * Blood tests for routine chemistries and for gene studies related to eating behaviors. * Questionnaires and interviews about the adolescent s general health and eating habits. * Acclimatization to test meal conditions for the study. The adolescent is given a breakfast shake to drink.

Participants come to the NIH Clinical Center at 10:30 AM for laboratory meal testing. At this visit, the adolescent does the following:

* Eats food from a buffet of everyday foods that most kids eat. * Fills out questionnaires. * Tastes and rates the flavor of a variety of snack foods.

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Key information

Conditions

Overweight Behavior Behavior, Animal Binge Eating Body Weight Bulimia Eating Behavior Feeding Behavior Hyperphagia Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Pathological Conditions, Signs and Symptoms Signs and Symptoms Signs and Symptoms, Digestive

Age range

13 year–17 year

Sex eligibility

All sexes

Study type

Observational

Primary location

National Institutes of Health Clinical Center, 9000 Rockville Pike

Bethesda, Maryland, 20892, United States

About this study

Little is known about the eating behaviors that place adolescents at heightened risk for overweight. In the proposed study, we aim to investigate the role that eating behaviors and genes may play in the development of overweight. Participants will be adolescent girls and boys from a racially/ethnically diverse sample of adolescents from the DC Metro community. Adolescent eating behavior will be observed during laboratory test meals. Adolescents will be provided with a large buffet of foods or a standard meal and instructed to eat until you are no longer hungry. Thirty minutes later, they will taste and rate a variety of highly palatable snack foods. Blood tests will be conducted to examine genes related to eating behavior. Assessments also will include affective states, degree of hunger, degree of fullness, body image satisfaction, disordered eating attitudes and behaviors, and measures of interpersonal interactions.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

INCLUSION CRITERIA:

Volunteers will qualify for participation in the study if they meet the following criteria:

<TAB>Age 13-17 years.
<TAB>Good general health as indicated by medical history and physical examination.
<TAB>Negative urine glucose and normal electrolytes, hepatic, and thyroid function.
<TAB>For the fMRI portion only: right handedness (required for standardization of responses).
<TAB>For the fMRI portion only: female.
<TAB>For the fMRI portion only: overweight (BMI greater than or equal to 85th percentile for age and sex).

Exclusion criteria

Volunteers will be excluded if they have any of the following:

<TAB>Medical problem likely to affect caloric intake.
<TAB>History of any condition including psychiatric disorders in either child or their responsible parent that in the opinion of the investigators would impede competence to sign consent, interfere with adherence to procedures, or possibly hinder completion of the study.
<TAB>Pregnancy.
<TAB>Use of medication likely to affect caloric intake.
<TAB>History of significant neurological injury or insult.
<TAB>For the fMRI portion only: braces (or other metal) that would interfere with the fMRI procedure.
<TAB>For the fMRI portion only: non-native English speakers (required for standardization of responses).

Sponsors and collaborators

Lead sponsor

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Nih

Registry information

Important dates

Study start: 2008
Study completion: 2015
First posted: Mar 10, 2008
Registry last updated: Oct 6, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed