Early Exposure to Lead and Adult Antisocial Outcomes

Prior research indicates a link between early lead exposure and risk for delinquent behavior. In this study, we follow a large birth cohort from the Cincinnati Lead Study into early adulthood to determine whether this increased risk persists. Outcome measures include official arrest records, diagnoses of Substance Abuse Disorder and Antisocial Personality Disorder, self-report of delinquent behavior, and a psychopathy scale. Predictors include pre-natal and post-natal blood lead levels. Multivariate statistical methods will control for potential confounders/covariates.

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Key information

Conditions

Lead Poisoning Chemically-Induced Disorders Heavy Metal Poisoning Poisoning

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Children's Hospital Medical Center

Cincinnati, Ohio, 45229, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

(1) Part of original CLS birth cohort -

Exclusion criteria

(1) Moved out of geographic area

Treatment and study plan

Primary outcomes

Lead Exposure and Antisocial Behavior

Time frame: Prenatal (1-2 trimester) and postnatal on a quarterly and bi-annual basis (until 6.5 years)

Sponsors and collaborators

Lead sponsor

National Institute of Environmental Health Sciences (NIEHS)

Nih

Registry information

Important dates

Study start: 2001
Primary completion: 2006
Study completion: 2006
First posted: Feb 2, 2006
Registry last updated: Nov 18, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed