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OpenTrials
Completed

NCT Number: NCT02466139

Early Clinical, Laboratory and Microbiological Predictors of Treatment Outcomes in Infective Endocaridtis

The investigators conduct a prospective observational study on consecutive patients being admitted to a tertiary care-centre with infective endocarditis. The investigators' primary aim is to identify baseline clincal, laboratory and microbiological predictors of in-hospital events, mortality and 6-month mortality.

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Key information

Conditions

Infective Endocarditis Cardiovascular Diseases Endocarditis Heart Diseases

Sex eligibility

All sexes

Study type

Observational

About this study

Mortality and major complications among infective endocarditis remain high. In addition developing nations are crippled with a high incidence of culture-negative endocarditis and lack of wide availability of transesophageal echocardiography. We intended to identify predictors among admission clinical features, laboratory paramters and culture reports that can help risk stratify patients early in the course of treatment.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Fulfillment of modified Duke criteria

Exclusion criteria

  • No consent
  • inadequate baseline data

Treatment and study plan

Primary outcomes

  1. In-hospital mortality

    Time frame: 30 days

  2. Major complications

    Time frame: 30 days

Secondary outcomes

  1. Number of patients who had embolic events

    Time frame: 30 days

  2. Number of patients who needed urgent cardiac surgery

    Time frame: 30 days

  3. Short term Mortality

    Time frame: 6 months

Sponsors and collaborators

Lead sponsor

Government Medical College, Kozhikode

Other

Registry information

Official study title

Early Clinical, Laboratory and Microbiological Predictors of Treatment Outcomes Among Infective Endocaridtis Patients in a Tertiary-care Centre in Kerala

Acronym: CRP-IE

Important dates

Study start
2012
Primary completion
2015
Study completion
2015
First posted
Jun 9, 2015
Registry last updated
Jun 9, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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