Dynamic and Static Autoregulation After Brain Injury

The aim of the study assesses static and dynamic cerebrovascular autoregulation daily over one week in patients with traumatic brain injury or intracranial hemorrhage to quantify the temporal profile of the autoregulatory status.

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Key information

Conditions

Acute Brain Injuries Brain Diseases Brain Injuries Brain Injuries, Traumatic Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Craniocerebral Trauma Hemorrhage Intracranial Hemorrhages Nervous System Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms TBI (Traumatic Brain Injury) Trauma, Nervous System Vascular Diseases Wounds and Injuries

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University Medical Center of the Johannes Gutenberg-University Mainz

Mainz, 55131, Germany

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Traumatic brain injury
Intracranial hemorrhage

Exclusion criteria

Measurement of TCD were impossible
Injury of the legs (if the both tigh cuffs for dynamic autoregulation could not be fixed)

Treatment and study plan

There are no interventions in this study

Other

Primary outcomes

Disturbed cerebrovascular autoregulation after brain injury

Time frame: 7 days

Sponsors and collaborators

Lead sponsor

Johannes Gutenberg University Mainz

Other

Registry information

Official study title

Serial Measurement of Static and Dynamic Cerebrovascular Autoregulation After Brain Injury

Important dates

Study start: 2001
Primary completion: 2009
Study completion: 2010
First posted: Feb 17, 2010
Registry last updated: Aug 22, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed