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OpenTrials
Completed

NCT Number: NCT07380607

Double Triggering Asynchrony in Mechanically Ventilated Patients.

This observational study examined double triggering asynchrony in28ICU patients on mechanical ventilation. Researchers collected data on patient characteristics, health conditions, and outcomes to understand how this problem affects critically ill patients. Findings may help improve ventilator care in intensive care units.

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Key information

Conditions

Respiratory Failure Critical Illness Disease Attributes Mechanical Ventilation Pathologic Processes Pathological Conditions, Signs and Symptoms Patient-Ventilator Asynchrony Respiration Disorders Respiratory Insufficiency Respiratory Tract Diseases Signs and Symptoms Signs and Symptoms, Respiratory

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Specialised Medical Hospital - ICU

Al Mansurah, Dakahlia Governorate, 35516, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adult ICU patients aged ≥18 years receiving invasive mechanical ventilation
  • Documented double triggering asynchrony on ventilator waveform analysis.

Exclusion criteria

  • Patients with contraindications to diaphragmatic ultrasound, including thoracic or abdominal surgery.
  • Patients with known diseases affecting diaphragmatic function, such as Duchenne muscular dystrophy (DMD) or myasthenia gravis (MG).
  • Patients with advanced chronic liver disease (Child-Pugh class C)
  • Patients with chronic increased intra-abdominal pressure.
  • Patients with moderate to massive pleural effusion.
  • Patient or legal guardian refusal to participate in the study.

Treatment and study plan

Primary outcomes

  1. Sensitivity of diaphragmatic ultrasound for detection of double triggering asynchrony

    Time frame: During ICU admission, at the time of double triggering detection by ventilator graph interpretation

    Proportion of double triggering asynchrony events correctly identified by diaphragmatic ultrasound compared with ventilator waveform analysis as the reference standard

Sponsors and collaborators

Lead sponsor

Mansoura University

Other

Registry information

Official study title

Sensitivity of Diaphragmatic Ultrasonography in Detecting Double Triggering Asynchrony in Mechanically Ventilated ICU Patients.

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Feb 2, 2026
Registry last updated
Apr 15, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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