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NCT Number: NCT06825338

Does the 'CATCH My Breath' Vaping Prevention Program Prevent High School Students in Ontario, Canada From Starting to Vape?

Vapes (also called e-cigarettes) have increased in popularity among youth in Canada and the United States. Youth who try vaping are at risk of becoming addicted and continuing to vape. To help combat the rise in vaping, there is an urgent need to identify effective ways to prevent youth from experimenting with vaping. Because of the novelty of vapes, there are few school-based programs targeting vaping. This study will investigate whether a vaping prevention curriculum called 'CATCH My Breath' (CMB) prevents high school students from starting to vape.

The investigators will recruit 28 schools in Ontario, Canada into the intervention group, and students at these schools will be presented with the CMB curriculum by Public Health Unit staff. CMB is an evidence-based program that includes two 60-minute lessons that provide students with information about social norms related to vaping, health risks of vaping, media literacy, and in-class activities to practice refusal skills. Students will complete an online survey before being exposed to the curriculum, 3-months later, and 12-months later. The vaping behaviours of these students will be compared to students in a separate study of youth health (i.e., the COMPASS study) who are not given the curriculum.

Evidence from this study will identify whether students exposed to CMB are less likely to start and continue vaping. If effective, CMB can be easily delivered in high schools across Canada in order to reduce the number of students who vape.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Vaping Behaviors Behavior Smoking Vaping

Age range

13 year–19 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hastings and Prince Edward District School Board, Belleville, Ontario, Canada

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About this study

Background and Importance: Youth vaping (or e-cigarette use) as increased dramatically among youth populations in Canada and the United States. While the long-term negative effects of vaping are relatively unknown, youth who vape are at risk of becoming addicted to nicotine and continuing to vape. Given the novelty of these devices and their rising popularity among youth, there is an urgent need to identify effective prevention approaches.

Research Aims: The goal of this study is to investigate the effectiveness of the 'CATCH My Breath' (CMB) vaping prevention curriculum at preventing vaping initiation among a cohort of high school students in Ontario, Canada. Specifically, this study will identify whether students exposed to CMB have a lower likelihood of 1) initiating vaping, 2) being susceptible to future vaping, and 3) vaping in the past 30-days at 12-month follow-up, compared to a matched comparison group of students. This study will also investigate whether the effects of the intervention differ according to gender. Methods: Intervention. CMB is a school-based vaping prevention curriculum based on best practices from earlier prevention studies and incorporates theory to foster social competence and social influence resistance skills. It is delivered through two 60-minute lessons delivered by a trained presenter. A pilot study identified components of the program that worked well and what needed to be adapted for a Canadian high school context. Sample. A purposive sample of 28 high schools in Ontario will be recruited and Public Health staff will deliver the curriculum to grade 9 students during Physical Education & Health classes. A matched sample of 28 high schools from a larger pool of schools participating in a separate study of youth health (i.e., the COMPASS study) will be selected as a comparison group. A matched sample of students will be identified from comparison group schools. Data collection & analysis. Students in the intervention group (n=2800) will complete an online survey before exposure to the curriculum and 3-months, and 12-months later to identify changes in vaping knowledge, attitudes, and behaviour. Descriptive analysis of baseline data will produce a profile of demographics and baseline characteristics and identify any imbalances between the intervention and comparison groups that should be accounted for in later analyses. Multilevel regression models will test for intervention effects while controlling for baseline differences through the use of covariates. Expected Outcomes: Evidence from this project will identify whether students exposed to CMB are less likely to start vaping, which will support school-based efforts to prevent vaping initiation and experimentation among youth.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

School Inclusion Criteria:

  • public and private schools in Ontario, English-speaking schools, include students in grades 9 through 12, operate in a standard school/classroom setting (i.e., not a virtual school)

School Exclusion Criteria:

  • non-English speaking schools, virtual schools, currently using the CATCH My Breath vaping prevention curriculum

Student Inclusion Criteria:

  • enrolled in the class in which the CATCH My Breath curriculum is being delivered

Student Exclusion Criteria:

  • not enrolled in the class in which the CATCH My Breath curriculum is being delivered

Treatment and study plan

CATCH My Breath

Other

CATCH My Breath (CMB) is a school-based vaping prevention curriculum based on best practices from earlier prevention studies that works by fostering social competence and social influence resistance skills. The curriculum design and content targets two key constructs of Social Cognitive Theory: self-efficacy and behavioural capacity (i.e., knowledge and skills). The curriculum provides students with knowledge of why and how to resist vaping. It is delivered through two 60-minute lessons by a trained Public Health Unit presenter. The curriculum lessons provide information about: 1) the physical, mental, and addiction risks associated with vaping, 2) social norms of vaping (e.g., most youth don't vape), 3) media literacy (e.g., how to recognize and decipher marketing of vapes), 4) strategies to resist and avoid vaping, 5)school and provincial policies about vaping. To solidify the content, in-class activities allow students to discuss what they are learning and practice refusal skills.

Other names: Vaping prevention program, Vaping prevention curriculum

Primary outcomes

  1. Number of participants that initiate vaping at 12-month follow-up

    Time frame: baseline and 12-month follow-up

    One validated item will assess ever vaping: "Have you ever tried a vape, also known as an e-cigarette?", with response options 'Yes' and 'No'. This item is consistent with other youth health surveillance studies in Canada and the US and is already present in the COMPASS survey. The question will include a definition of vapes, including examples and images of common brands, to improve the validity of student responses. Students who respond 'No' at baseline will be categorized as 'Never vapers'. Students who never vaped at baseline who respond 'Yes' at follow-up will be categorized as 'Initiated vaping' (outcome of interest), while those who respond 'No' at follow-up will be categorized as 'Did not initiate vaping' (reference group).

Secondary outcomes

  1. Change in susceptibility to future vaping from baseline to 12-month follow-up

    Time frame: baseline and 12-month follow-up

    Three validated items will assess susceptibility to future vaping among students who never vaped: (1) "Have you ever been curious about using a vape?"; (2) "If one of your best friends were to offer you a vape, would you use it?"; and (3) "At any time during the next year do you think you will use a vape?", with response options 'Definitely yes', 'Probably yes', 'Probably not', and 'Definitely not'. Consistent with previous studies, students who never vaped who respond 'definitely not' to all three questions will be considered 'Not susceptible to future vaping', while all others are considered 'Susceptible to future vaping'. The analyses will explore whether intervention group students who are susceptible to future vaping at baseline are more likely to become not susceptible to future vaping at follow-up relative to comparison group students.

  2. Change in number of students reporting past 30-day vaping from baseline to 12-month follow-up

    Time frame: baseline and 12-month follow-up

    One item will assess current (past 30-day) vaping: "On how many of the last 30 days did you use a vape?" (None, 1 day, 2 to 3 days, 4 to 5 days, 6 to 10 days, 11 to 20 days, 21 to 29 days, 30 days [every day]). Students who report vaping at least one day in the last 30 days will be categorized as 'Current vapers', while all others will be categorized as 'Non-current vapers'. The analyses will explore whether intervention group students who currently vape at baseline are more likely to not currently vape at follow-up relative to comparison group students.

  3. Change in knowledge of vaping-related harms from baseline to 3- and 12-month follow-up

    Time frame: baseline, 3-month, and 12-month follow-up

    Students in the intervention group will answer questions assessing knowledge of harms of vaping (9 items related to content delivered in the lessons), perceived positive and negative outcomes of vaping (11 items), subjective norms of vaping (2 items that ask about norms of vaping among their peers), and vaping resistance self-efficacy (4 validated items).

Sponsors and collaborators

Lead sponsor

University of Ontario Institute of Technology

Other

Collaborators

  • CATCH Global Foundation
  • Ontario Agency for Health Protection and Promotion
  • The University of Texas Health Science Center, Houston
  • University of Waterloo

Registry information

Official study title

Investigating the Effectiveness of the 'CATCH My Breath' Vaping Prevention Curriculum at Preventing Vaping Initiation Among High School Students in Ontario, Canada

Important dates

Study start
2025
Primary completion
2028
Study completion
2028
First posted
Feb 13, 2025
Registry last updated
May 1, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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