Does Surgical Treatment of Cartilage Defects Prevent Osteoarthritis in Later Life?

Observational study to assess the effectiveness of cell therapy for the treatment of osteoarthritis

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Osteoarthritis (OA) Arthritis Joint Diseases Musculoskeletal Diseases Osteoarthritis Rheumatic Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

Robert Jones and Agnes Hunt Orthopaedic hospital, Oswestry, United Kingdom

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

ACI patients or patients receiving an alternative treatment

Exclusion criteria

Anyone who does not meet the inclusion criteria

Treatment and study plan

Primary outcomes

Cell Therapy Questionnaire

Time frame: At least fifteen months post operation

Cell Therapy Questionnaire CTQ

Sponsors and collaborators

Lead sponsor

Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust

Other Gov

Collaborators

Keele University

Registry information

Official study title

Cell Therapy for Osteoarthritis

Acronym: REACT

Important dates

Study start: 2010
Primary completion: 2030
Study completion: 2030
First posted: Jan 6, 2026
Registry last updated: Jan 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Recruiting