Discard:Characterisation of Colonic Polyps in Vivo

Prospective study of accuracy of colonic polyp characterisation in vivo using high resolution white light endoscopy, narrow band imaging and chromoendoscopy.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Colorectal Polyps Colonic Diseases Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Neoplasms Neoplasms by Site Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Polyps Rectal Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Wolfson Unit for Endoscopy, St Mark's Hospital

Harrow, Moddlesex, HA1 3UJ, United Kingdom

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients over 18 years of age, assessed as fit for routine colonoscopy
Patients attending for screening or surveillance colonoscopy meeting the following criteria:

Polyp surveillance with at least 3 adenomas or 1 adenoma>10mm at previous colonoscopy
Surveillance post colorectal cancer resection
Screening with positive faecal occult blood test

Exclusion criteria

Patients with known colitis or polyposis syndromes
Unable or unwilling to give informed consent

Treatment and study plan

Primary outcomes

Accuracy of polyp characterisation

Time frame: 12 months

Secondary outcomes

Change in surveillance interval after formal histopathology

Time frame: 12 months

Sponsors and collaborators

Lead sponsor

Imperial College London

Other

Registry information

Official study title

Characterisation of Small Colonic Polyps in Vivo

Acronym: DISCARD

Important dates

Study start: 2008
Primary completion: 2009
Study completion: 2009
First posted: Apr 28, 2009
Registry last updated: Aug 5, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed