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NCT Number: NCT07044895

Diode Laser Photocoagulation With Immediate Implant Placement

Placement of an immediate implant is becoming popular because of its potential in minimizing the treatment time and enhancing the patient comfort and esthetic outcomes. It is crucial to maintain adequate thickness of labial bone with the establishment of a stable and healthy gingival seal around the implant abutment to prevent the invasion of bacteria and peri-implant inflammation. Diode lasers have been developed as a promising tool in dentistry, providing a precise manipulation and photocoagulation effect that may have a positive influence on both bone remodeling and soft tissue healing. This study aims to evaluate the effectiveness of the utilization of diode laser photocoagulation with immediate implant placement and customized healing abutment in the maxillary esthetic zone.

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Key information

Conditions

Tooth Extraction Immediate Dental Implant Maxillary Esthetic Zone Photocoagulation

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Dentistry clinics, Beirut Arab University

Beirut, Lebanon

Location contact

Amina R Ali, BDS

CONTACT

Amina R Ali, BDS

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with non-restorable maxillary teeth in the aesthetic zone are indicated for extraction and subsequent immediate implant placement, including those with:
  • A severely carious tooth that cannot be restored.
  • Pulpal necrosis or irreversible pulpitis that is not amenable to endodontics.
  • Periodontally involved teeth with grade 2 mobility or above.
  • Teeth with root caries that can't be restored.
  • Patients with an extraction socket Type I.
  • A good standard of oral hygiene.

Exclusion criteria

  • Patients with extraction socket Type II or III, with buccal plate defects.
  • Absence of at least 2 mm of bone apical to the extraction socket
  • tooth ankylosis.
  • Patients with deciduous teeth.
  • Heavy smokers.
  • Systemic conditions
  • History of oral or intravenous bisphosphonate therapy or any treatments with other medications that may interfere with bone metabolism within the past 12 months

Treatment and study plan

Diode laser and Immediate implant

Other

patients with non-restorable teeth in the maxillary esthetic zone will be included in this prospective single-arm study. The non-restorable tooth will be atraumatically extracted and immediate implant placement will be placed. The extraction socket will be sealed with diode laser photocoagulation and customized healing abutments fabrication.

Primary outcomes

  1. Change in pain socres

    Time frame: at 7, 14, and 21 days

    Pain will be evaluated, using visual analogue scale (VAS) as follows:

    (0-1= None, 2-4= Mild, 5-7= Moderate, 8-10= Severe)

  2. Change in wound healing

    Time frame: at 7, 14, and 21 days

    The wound healing will be assessed based on Landry Wound Healing Index. The Landry Index uses a numerical score based on the assessment of four given parameters (Erythema, Edema, Wound Margin Adaptation, and Presence of Exudate). Each parameter is given a score depending on its severity, and the total score determine an overall evaluation of wound healing

  3. Change in implant stability

    Time frame: baseline and 6 months

    The base line primary Implant Stability Quotient (ISQ) will be measured during the operative stage, while the secondary stability quotient will be measured 6-months post-operative during the prosthetic phase preparation.

Secondary outcomes

  1. Change in Crestal Alveolar Process width

    Time frame: baseline and 6 months

    The width of the crestal alveolar process will be assessed by determination of the dimensional changes of Bucco-palatal ridge in the 6 months' scan

  2. Change in labial bone thickness

    Time frame: baseline and 6 months

    The overall persistence of the labial plate of bone after the atraumatic extraction and immediate implant placement will be evaluated by the assessment of the thickness labial plate of bone in the scan performed after 6 months and comparing it with the preoperative CBCT record. The distance will be measured from the root surface to the outer buccal bone surface in the preoperative CBCT record. Measurements will be performed on the cross-sectional cut of the CBCT at three levels; crestal labial thickness, middle labial thickness, and apical labial thickness.

  3. Change in esthetic of soft tissue

    Time frame: at 1 month

    The pink esthetic score (PES) introduced by Furhauser et al will be used for evaluation of the esthetic outcome of soft tissue surrounding single crowns supported by implant in the esthetic zone. The PES consists of seven factors each one is given a score of 2, 1, or 0, and a total score will be ranging between 0 and 14

Study contacts

Contact information is provided by the study sponsor or research team.

Amina R Ali, BDS

CONTACT

[email protected]

+961 70 908 487

Sponsors and collaborators

Lead sponsor

Hams Hamed Abdelrahman

Other

Registry information

Official study title

Evaluation of Diode Laser Photocoagulation With Immediate Implant Placement in the Maxillary Esthetic Zone

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jul 1, 2025
Registry last updated
Jul 1, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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