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Completed

NCT Number: NCT06428318

Diagnostic Value of the Biofire®in Community Acquired Pneumonia

This study aimed to determine the impact value of the BioFire FilmArray Pneumonia panel compared to conventional sputum culture in critically ill patients with pneumonia.

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Key information

Conditions

Pneumonia Infections Lung Diseases Respiratory Tract Diseases Respiratory Tract Infections

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Ain Shams University

Cairo, Abassia, Egypt

About this study

the BioFire® FilmArray Pneumonia Panel (BFPP) emerges as a promising candidate for a rapid and multifaceted diagnostic approach.

This study compare the diagnostic accuracy, turnaround time, and impact on antibiotic management decisions of BFPP versus conventional sputum culture in critically ill patients admitted to the ICU with suspected pneumonia.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients admitted to the ICU with community acquired pneumonia

Exclusion criteria

  • Age less than 18 years old.
  • End stage malignant patients,
  • Patients admitted to the ICU with Acute Lung Injury (ALI).
  • Patients admitted to the ICU with Acute Respiratory Distress Syndrome (ARDS).
  • Patients with radiological findings suggesting atypical pneumonia.
  • Immunocompromised as defined by HIV/AIDS, known immunodeficiency, chronic steroids > 20mg/day Prednisone equivalent, other immunosuppressants.
  • Solid organ or bone marrow transplant patients, cystic fibrosis.
  • Unstable psychiatric or psychological condition rendering the subject unlikely to be cooperative or to complete the study requirements.

Treatment and study plan

Conventional Sputum culture

Diagnostic Test

Sputum culture was done to patients and they received Antibiotics According to its results

BioFire Pneumonia Panel (BFPP)

Diagnostic Test

BioFire Pneumonia Panel (BFPP) was done to patients and they received Antibiotics According to its results

Primary outcomes

  1. the ICU length of stay

    Time frame: Five days after admission

    The potential correlation between the use of BFPP and its relation to the ICU length of stay

Sponsors and collaborators

Lead sponsor

Ain Shams University

Other

Registry information

Official study title

Diagnostic Value of the Biofire® Filmarray Pneumonia Panel Compared to Conventional Sputum Culture in Critically il Patients With Pneumonia

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
May 24, 2024
Registry last updated
May 29, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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