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Completed

NCT Number: NCT07070271

Effect of Neurophysiological Facilitation of Respiration on Blood Gases and Hospital Stay in Children With Pneumonia

The goal of this clinical trial is to investigate the effect of respiratory neurophysiological facilitation techniques on arterial blood gases, the severity of respiratory illness and duration of hospital stay in hospitalized children with pneumonia.

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Key information

Conditions

Pneumonia Infections Lung Diseases Respiratory Tract Diseases Respiratory Tract Infections

Age range

6 month–2 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Cairo university specialized pediatric hospital (Abo-El Reesh)

Giza, Egypt

About this study

Children who were hospitalized with a clinically and radiologically confirmed diagnosis of pneumonia will participate in this study. Selected Patients will be randomly assigned into two groups of equal number.

One group will only receive conventional chest physical therapy program in form of (postural drainage, chest percussion, vibration and suction if needed). The other group will receive conventional chest physical therapy program along with respiratory neurophysiological facilitation techniques in form of (anterior basal lift, intercostal stretch, abdominal co-contraction).

All patients will receive the treatment program once a day for successive 5 days.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Children of both sexes, with age ranged from 6 months to 2 years old.
  • All children diagnosed with pneumonia.
  • All children should be vitally stable during the study period.

Exclusion criteria

  • Medically unstable children.
  • Children with uncontrolled convulsions.
  • Children with Osteopenia.

Treatment and study plan

Respiratory neurophysiological facilitation techniques

Other

The respiratory neurophysiological facilitation techniques in form of (anterior basal lift, intercostal stretch, abdominal co-contraction) once a day for 5 days.

conventional chest physical therapy

Other

conventional chest physical therapy program in form of (postural drainage, chest percussion, vibration and suction if needed) once a day for 5 days.

Primary outcomes

  1. Arterial blood gases

    Time frame: At baseline (after enrollment and before the first chest physiotherapy session) and on day 5 after completing the fifth session, assessed within 5 days of enrollment

    Blood gas analysis is a commonly used diagnostic tool to evaluate the partial pressures of gas in blood and acid-base content.

    The blood sample is collected from the radial artery or the femoral artery.

  2. Duration of hospitalization

    Time frame: From the date of hospital admission until the date of discharge, up to 20 days

  3. The severity of respiratory distress

    Time frame: At baseline (after enrollment and before the first chest physiotherapy session) and on day 5 after completing the fifth session, assessed within 5 days of enrollment

    Using the Pediatric Respiratory Severity Score to assess respiratory rate, wheezing, accessory muscle use, SpO2, and feeding difficulties.

    Each component was given 0 or 1 point and the total score was classified as mild (0-1 points), moderate (2-3 points), or severe (4-5 points)

Sponsors and collaborators

Lead sponsor

Asmaa Ahmed Abd El-samad

Other

Registry information

Official study title

Effect of Neurophysiological Facilitation of Respiration on Blood Gases and Duration of Hospitalization in Children With Pneumonia

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jul 17, 2025
Registry last updated
Jul 1, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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