Assiut university hospital
Asyut, Assuit, Assuit universi, Egypt
NCT Number: NCT04726436
The aim of this study to assess which time and dose of dextrose solution more effective in decreasing postoperative nausea and vomiting.
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Notify Me18 year–65 year
Female
Interventional
Not applicable
Asyut, Assuit, Assuit universi, Egypt
All patients signed informed consent after excluding patients not candidate for the study.patients were divided to three groups, taking either 0.9% saline as control group(group C), dextrose 5%(group D5) or dextrose 10%(group D10).
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
One hour before operation, patients were given dexrose 5%100/hour only for 2 hours to end at about middle of surgery
One hour before operation, patients were given dexrose 10 %100/hour only for 2 hours to end at about middle of surgery
One hour before operation, patients were given normal saline100/hour only for 2 hours to end at about middle of surgery
Other names: Normal saline
Time frame: 24hour after surgery
Number of participants who experienced PONV grade ≥2 as assessed by PONV score . The PACU nurses assessed and documented PONV using a Verbal Descriptive Scale, which correlates to visual analog nausea scores, with an objective measure of severity: 0 = no PONV: patient reports no nausea and has had no emesis episodes; 1 = mild PONV: patient reports nausea but declines antiemetic treatment; 2 = moderate PONV: patient reports nausea and accepts antiemetic treatment; and 3 = severe PONV: nausea with any emesis episode (retching or vomiting). The score was obtained at 0, 30, 60, 90, and 120 minutes after PACU arrival; thus 5 scores were recorded during PACU stay. A 24-hour PONV assessment that elicited any nausea and emesis episode since PACU discharge was obtained by a blinded investigator by telephone or in person at the patient's bedside (delayed PONV).
Time frame: 24hour postoperative
Frequency of doses of antiemetics required to control postoperative nausea and vomiting, initial antiemetic treatment was 10 mg slow IV metoclopramide for occurred nausea or 4 mg IV ondansetron for occurred nausea & vomiting or if the previous treatment failed for nausea
Time frame: 24 hour postoperative
Frequency of classes of antiemetics required to control postoperative nausea and vomiting, Initial antiemetic treatment was 10 mg slow IV metoclopramide for occurred nausea or 4 mg IV ondansetron for occurred nausea & vomiting or if the previous treatment failed for nausea
Assiut University
Other
The Impact of Timing and Dosing of Dextrose Solution on Postoperative Nausea and Vomiting.
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