Dexmedetomidine Infusion in Hypospadias Surgery

The investigators hypothesize that giving Dexmedetomidine in combination with Fentanyl for pediatric patients undergoing hypospadias surgery, will reduce the fentanyl requirement for intraoperative and postoperative analgesia.

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Key information

Conditions

Pain Neurologic Manifestations Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

1 year–12 year

Sex eligibility

Male

Study type

Interventional

Phase

Phase 3

Primary location

Jordan University Hospital

Amman, 11942, Jordan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Children aged 1-12 years undergoing hypospadias repair

Exclusion criteria

Allergy to Dexmedetomidine
Preoperative use of sedatives or analgesics
cardiac diseases
Children with mental retardation

Treatment and study plan

Dexmedetomidine and Fentanyl

Drug

Dexmedetomidine in a dose of 1 ug/kg initial dose then continuous infusion of 0.7 ug/kg/hr . Combined with Fentanyl at a dose of 2 ug/kg initially plus boluses of fentanyl to keep the patient hemodynamically stable.

Other names: Precedex

Fentanyl

Drug

This group received Fentanyl at a dose of 2 ug/kg initially, followed by boluses to keep the patient hemodynamically stable.

Primary outcomes

Intraoperative and postoperative fentanyl requirement (in microg/kg)

Time frame: 6/2008-1/2009

Sponsors and collaborators

Lead sponsor

University of Jordan

Other

Registry information

Official study title

An Intraoperative Infusion of Dexmedetomidine Reduces the Opioid Requirements for Pediatric Patients Undergoing Hypospadias Surgery

Important dates

Study start: 2008
Study completion: 2009
First posted: Jun 23, 2009
Registry last updated: Jun 23, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed