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NCT Number: NCT06899841

Dexmedetomidine in Sonographic Guided Erector Spinae Plane Block

to investigate the postoperative analgesic effect of dexmedetomidine addition with different doses as an adjuvant to bupivacaine to Erector spinae plane block after renal surgeries.

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Key information

Conditions

Pain Management Agnosia Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Pathological Conditions, Signs and Symptoms Perceptual Disorders Signs and Symptoms

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2 / Phase 3

Primary location

Assiut University Hospitals

Asyut, Assiut Governorate, 71111, Egypt

Location status: Recruiting

Location contact

Mahmoud Adel Faisal, lecturer

CONTACT

[email protected]

01004391577

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age between 18 and 70 years.
  • Both sexes, males and females.
  • Patients with the American Society of Anesthesiologists (ASA) physical status I/II.
  • Body mass index (BMI) of 18-35 kg/m2
  • Patients scheduled for elective Renal or Percutaneous Nephrolithotomy.

Exclusion criteria

  • Patients under 18 years.
  • Patient refusal of nerve block.
  • Infection at the site of injection.
  • Coagulopathy.
  • Allergy to used medications.
  • Psychiatric disorder or chronic pain syndromes.
  • Chronic opioid use or substance abuse.
  • Quadriplegic patients.

Treatment and study plan

Dexmedetomidine

Drug

different doses of dexmedetomidine added to bupivacaine in erector spinae plane block

Primary outcomes

  1. postoperative analgesic duration

    Time frame: 24 hours

    postoperative analgesic duration with each dose

Secondary outcomes

  1. Pain score

    Time frame: 24 hours

    severity of pain using visual analogue pain score

  2. side effects

    Time frame: 24 hours

    as hemodynamic effect as (hypotension, bradycardia), nausea and vomiting.

  3. dynamic pain score

    Time frame: 24 hours

    Dynamic visual analogue pain score (pain with cough, deep breath, and movement)

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Effect of Different Doses of Dexmedetomidine Added to Local Anesthetic in Sonographic Guided Erector Spinae Plane Block for Pain Management After Renal Surgeries : Randomized Clinical Trial

Important dates

Study start
2024
Primary completion
2025
Study completion
2026
First posted
Mar 28, 2025
Registry last updated
Mar 28, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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