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OpenTrials
Completed

NCT Number: NCT05090956

Developpement of 3T MRI Protocol

Since January 2010, a new magnetic resonance imaging scanner (Philips 3T, Achieva) is installed on the Baudot Building in Toulouse hospital. This tool, is completely dedicated to the research. It was installed with sequences RMN supplied by the manufacturer.

Imagers also contain an instrumentation susceptible to evolution and/or to adjustment (antennas radio frequency, sheath of gradients, elements of physiological monitoring (for example control of the breath), regulation of the homogeneity of the magnetic field).

This MRI scanner and this instrumentation are used for anatomical examinations or for paradigms of cognitiveresearch (for example of detection of intellectual activations following simple stimuli of fingers movement, visual tasks, or of mental processes).

The developpement of this equipment is going to favor the emergence of numerous projects and new themes, up to there adressed by other techniques (psychophysics, EEG).

To obtain good quality signals and know the practical limits of this imager, it is thus necessary that the researchers doctors, physicists and engineers, can finalize on volunteers' significant number, all the sequences RMN necessary for the use of these tools for the research.

These developments are going to get organized around four main axes:

1 the control of the geometrical distortions (generated by the introduction of an object within the magnetic field) 2 Optimization of the parameters of sequences to improve the contrast and the spatial resolution of the obtained images 3 the development of new sequences 4 the feasibility study of the protocols of functional MRI

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Key information

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Healthy adult, age = 18 years;

  • Visual, hearing , oral or written capacities and expression sufficient for the suitable realization of the tests;
  • Obtaining of the informed consent of the subject.

Exclusion criteria

  • Subjects presenting a neurological, psychiatric history;
  • Subjects under chronic medication which can influence the intellectual activity;
  • Subjects presenting a contraindication to the MRI (carriers of a pacemaker, an implanted material(equipment) activated by an electric, magnetic or mechanical system, carriers of haemostatic clips of anévrysmes intracérébraux or carotid arteries, carriers of orthopaedic, claustrophobic implants);
  • Subjects refusing to be informed about the possible presence of an anatomical anormality;
  • administrative Problems: impossibility to give about the information, no insurance, refusal to sign the consent, under guardianship subject ;
  • Subjects participating in another protocol • pregnancy

Treatment and study plan

MRI

Other

Primary outcomes

  1. Assessment of distortion of MRI images

    Time frame: 90 months

  2. Measurement of contrasts of MRI sequence

    Time frame: 90 months

    By using available software such as MRICro, Image J, Matlab or other post-processing tools developed as required

  3. Measurement of MRI sequence resolution

    Time frame: 90 months

    To estimate the resolution by measuring the signal-to-noise ratio using standard software such as MRICro, Image J, Matlab or other post-processing tools developed as required

Sponsors and collaborators

Lead sponsor

Institut National de la Santé Et de la Recherche Médicale, France

Other Gov

Registry information

Official study title

Mise au Point de Protocoles RMN Sur l'Imageur Philips 3T installé Sur le Site du Pavillon Baudot du CHU Purpan à Toulouse

Acronym: (MISAP)

Important dates

Study start
2012
Primary completion
2020
Study completion
2020
First posted
Oct 25, 2021
Registry last updated
Jul 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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