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OpenTrials
Active, Not Recruiting

NCT Number: NCT03473795

Developing Non-Communicable Disease Registries in Africa : A Step Towards Providing Quality Data for Improving Patient Outcomes

This umbrella protocol seeks to develop robust data registries for non-communicable diseases (NCDs) in sub-Saharan Africa (SSA) with the aim of providing accurate and comprehensive data for the evaluation of such diseases in sub-Saharan African countries.Healthy volunteers will be included in the study for comparison.

Additionally, the investigators aim to describe the gut microbiome community diversity of a cohort of community dwelling Nigerians and compare with CRC patients in Nigerian and at MSK. We will collect stool for microbiome and metabolomic analysis from community dwelling persons in the catchment area of ARGO facilities in Nigeria while contemporaneously administering an extensive medical and environmental exposure questionnaire.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Non-communicable Disease Disease Attributes Noncommunicable Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

National Hospital of Abuja (Data collection only), Abuja, Central Business District, Nigeria

Loading trial locations.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18 and older.
  • Suspected or confirmed diagnosis of a non-communicable disease. OR
  • Healthy volunteers/no confirmed diagnosis for comparison.

Exclusion criteria

  • Participants unwilling to sign consent.
  • Participants under the age of 18

Treatment and study plan

Questionnaire forms

Behavioral

The questionnaires will include information such as socio-demographic data, risk factors, disease specific data, investigation and treatment details as well as findings during followup. Particular reference will be made to outcome measures such as local and distant recurrence, survival and mortality.

Bio-specimen samples

Other

Samples can include tissue, blood, urine, saliva, hair and nail clipping.

Primary outcomes

  1. # of patients that develope non-communicable diseases in Africa

    Time frame: 5 years

Sponsors and collaborators

Lead sponsor

Memorial Sloan Kettering Cancer Center

Other

Collaborators

  • Duke University
  • Johns Hopkins University

Registry information

Official study title

Developing Non-Communicable Disease Registries in Africa: A Step Towards Providing Quality Data for Improving Patient Outcomes

Important dates

Study start
2018
Primary completion
2027
Study completion
2027
First posted
Mar 22, 2018
Registry last updated
Jun 9, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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