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OpenTrials
Completed

NCT Number: NCT00152659

Developing Criteria for Cortical Resections

The purpose of this study is to study how disease processes like tumors or epilepsy spread in the brain.

Completed

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Key information

Conditions

Epilepsy Brain Diseases Central Nervous System Diseases Neoplasms Nervous System Diseases Tumor

Sex eligibility

All sexes

Study type

Observational

Primary location

The University of Chicago Hospitals, The University of Chicago Comer Children's Hospital

Chicago, Illinois, 60637, United States

About this study

The purpose of this study is to study how disease processes like tumors or epilepsy spread in the brain. During surgery small pieces of abnormal (unusual) brain tissue may be removed. We analyze these specimens using more advanced microscopic and electrophysiologic techniques than are usually applied to such tissue specimens. In addition, some tissues can be maintained in laboratory conditions to allow analysis over the longer term. No extra brain tissue is taken to perform these studies. The tissue analysis is performed by the research team and are compared to the routine (normal) electrical recordings that are taken during this type of brain surgery. Currently there are no instructions telling a doctor how much brain tissue should be cut out to prevent the spread of tumors or epilepsy. We are hoping that the results of this study help us to better know how much brain tissue needs to be removed to prevent the spread of tumors or epilepsy.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Surgical candidates with epilepsy or brain tumor(s)

Treatment and study plan

Tissue sample (procedure/screening)

Procedure

Tissue sampling

Primary outcomes

  1. measure electrical activity in tissue sample

    Time frame: at tissue aremoval time

Sponsors and collaborators

Lead sponsor

University of Chicago

Other

Registry information

Official study title

Developing Functional and Structural Criteria for Cortical Resections

Important dates

Study start
1998
Primary completion
2022
Study completion
2022
First posted
Sep 9, 2005
Registry last updated
Apr 26, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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