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NCT Number: NCT07017491

Determination of Glycemic Index and Glycemic Load of Selected Melon Varieties in Healthy Adults

This crossover study aims to determine and compare the glycemic index (GI) and glycemic load (GL) of different melon varieties in healthy adults. Using glucose as the reference food, participants will consume test portions of each melon variety containing equivalent amounts of available carbohydrates.

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Key information

Conditions

Glycemic Index Glycemic Load

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

This crossover study aims to determine and compare the glycemic index (GI) and glycemic load (GL) of different melon varieties in healthy adults. Using glucose as the reference food, participants will consume test portions of each melon variety containing equivalent amounts of available carbohydrates. Blood glucose levels will be monitored at regular intervals over a 2-hour period. The glycemic response will be used to calculate GI and GL values for each melon type. The study is intended to inform dietary recommendations for blood glucose management.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy males and females aged 18-50 years. 2) Body mass index (BMI) :Normal BMI (18-24.9) 3) Willingness to follow dietary instructions and attend all testing sessions
  • Exclusion Criteria:
  • Individuals with known metabolic disorders (e.g., diabetes, metabolic syndrome).
  • Use of medications or supplements affecting blood glucose.
  • Allergy or intolerance to melon or glucose solutions.
  • Not able to co ordinate

Treatment and study plan

Orange candy melon (Cucumis melo)

Other

Participants will consume a portion of melon A containing 50g of available carbohydrates to evaluate postprandial glycemic response.

Rock melon ( Cucumis melo var.cantalupensis)

Other

Participants will consume a portion of melon B containing 50g of available carbohydrates to evaluate postprandial glycemic response.

honey dew (cucumis melo L.)

Other

Participants will consume a portion of melon C containing 50g of available carbohydrates to evaluate postprandial glycemic response.

Primary outcomes

  1. Glycemic Index (GI) of Melon Varieties

    Time frame: 1 month

    The glycemic index of each melon variety will be calculated by comparing the incremental area under the blood glucose response curve (iAUC) over 2 hours after consumption of the test food, relative to glucose.

Secondary outcomes

  1. Glycemic Load (GL) of Melon Varieties

    Time frame: 1 month

    Calculated using the formula:

    Glycemic Load = (Glycemic Index × amount of carbohydrate in a typical serving) ÷ 100

Study contacts

Contact information is provided by the study sponsor or research team.

Naseer Ahmed

CONTACT

[email protected]

03305485960

Sponsors and collaborators

Lead sponsor

Rehman Medical Institute - RMI

Other

Registry information

Official study title

A Randomized, Open-Label, Cross-Over Study to Determine the Glycemic Index and Glycemic Load of Selected Melon Varieties in Healthy Adults

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jun 12, 2025
Registry last updated
Jun 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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