Determination of Glycaemic Index and Insulinaemic Index Values of 6 Food Products in 3 Separate Research Centers

This study will be performed at 3 centers and 15 subjects will be recruited at each center.

Inclusion criteria

• Aged 18-35 years inclusive.
• Non-smoker.
• BMI 19.0-25.0 kg/m2 inclusive.
• Healthy subjects with:

• Fasting plasma glucose < 5,6 mM (ADA criteria,2011)
• Insulin resistance index based on homeostasis model assessment (HOMA-IR) <1.70
• Fasting lipids: triglyceride <1.70mmol/L, LDL-cholesterol<5.00 mmol/L and HDL-cholesterol >1.03mmol/L for males or >1.29mmol/L for females (IDF criteria for metabolic syndrome, 2006)
• Gamma-GT, AST and ALT <1.5 times the upper limit of normal (ULN)
• Complete blood count: Normal full blood count according to the investigator
• Systolic blood pressure <130 mmHg
• Diastolic blood pressure <85 mmHg
• Resting heart rate 50-90 beats per minutes (after 3 minutes rest).
• Stable dietary habits; normal eating patterns; no history of eating disorders or strict dieting.
• Moderate level of physical activity (from basic daily activity to a high level of physical activity (regular physical activity at least 3 times per week))
• Able to fast for at least 10 hours the night before each test session.
• Able to refrain from eating legumes and drinking alcohol the day before each test session.
• Subject covered by social security or covered by a similar system
• Subject not taking any treatment for anorexia, weight loss, or any form of treatment likely to interfere with metabolism or dietary habits
• Subject having given written consent to take part in the study

Exclusion criteria

• Following a restrictive or specific diet.
• Suffering from any inflammatory or metabolic diseases
• Suffering from mental illness.
• Suffering from any food allergies or hypersensitivities (wheat, milk, egg, nuts, etc).
• Taking any regular prescription medication at the time of inclusion that should interfere with carbohydrate metabolism (except regular oral contraception medication, thyroid replacement therapy)
• Female who is pregnant (positive test results), lactating, planning pregnancy or not using acceptable contraceptive.
• Subject having taken part in another clinical trial within the last week.
• Subject currently taking part in another clinical trial or being in the exclusion period of another clinical trial.
• Subject undergoing general anaesthesia in the month prior to inclusion.
• Subject in a situation which in the investigator's opinion could interfere with optimal participation in the present study or could constitute a special risk for the subject.