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NCT Number: NCT06670157

Detachable Clip-assisted Endoscopic Cyanoacrylate Injection in the Treatment of Gastric Varices

A single-arm exploratory clinical study design was used to evaluate the safety and efficacy of a "modified sandwich injection" of tissue glue assisted by a detachable clip for the treatment of gastric varicose veins.

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Key information

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Eastern Theater General Hospital

Nanjing, Jiangsu, 210000, China

Location status: Recruiting

Location contact

yu chang, Master

CONTACT

[email protected]

18175226948

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • The subject voluntarily signs the informed consent for this experiment; According to clinical manifestation, laboratory examination, imaging examination, or liver biopsy in the diagnosis of liver cirrhosis patients; The endoscopy diagnosed gastric varices (gastroesophageal varices, gastroesophageal varices type 2 or type 1 isolated gastric varices type 1); High risk of gastric varices or has a history of gastric varices bleeding. The initial fluid resuscitation patients before or after the recovery hemodynamic stability; The age of 18 years old or more.

Exclusion criteria

  • < 18 years old; Regional portal hypertension; Always have a liver transplant, via the jugular intrahepatic portal vein system bypass or splenectomy combined varices cut-out art history; A concurrent hepatorenal syndrome and/or multiple organ failure; Significant impact on survival of malignant tumor; Pregnancy or lactation; A known allergy to iodine.

Treatment and study plan

Detachable Clip

Other

After the varicose vessels basically disappeared under the endoscope, the removable titanium clamp was removed

Primary outcomes

  1. Rebleeding rate at 6 weeks after treatment for gastric fundus varicose veins in cirrhosis

    Time frame: 6 weeks

Study contacts

Contact information is provided by the study sponsor or research team.

ji xuan, doctor

CONTACT

[email protected]

13140718720

yu chang, master

CONTACT

18175226948

Sponsors and collaborators

Lead sponsor

Yu Chang

Other

Registry information

Official study title

Detachable Clip-assisted Endoscopic Cyanoacrylate Injection in the Treatment of Gastric Varices Under X-ray Perspective

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Nov 1, 2024
Registry last updated
Nov 1, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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