Total caries removal
ProcedureTotal caries removal and application of bioactive material
Other names: Biodentin application
NCT Number: NCT07028905
This clinical trial will be conducted to clinical, radiographical and histological evaluation of pulp condition with reversible pulpities after total and selective removal of primary and secondary caries (randomized clinical trial and exo-vivo study)
Trial opening soon.
Get Notified18 year–40 year
All sexes
Interventional
Not applicable
Randomized clinical trial Sample size 144 case…
Randomization method used:
Sample size calculation was performed using R statistical analysis software version 4.3.2 for Windows
Outcome variables:
Pulp vitality and post operative pain Grouping classified into four groups as follows: The first group : total caries removal of primary caries(PTCR) 27 The second group: selective caries removal of primary caries(PSCR) The third group: total caries removal of secondary caries(STCR) The fourth group : selecive caries removal of secondary caries(SSCR)
Expected Time table:
2 years Recall of patient after 3,6,9 and 12 months 6 months for writing and 6 months for data analyzed
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
7- Patients with history of antibiotic or analgesics intake within few days of operative intervention. 8- Patients with previously root canal-treated teeth. 9- Periodontally compromised teeth. 10-Teeth that will be extracted for periodontal or orthodontic reasons as it will conduct for histological evaluation
Total caries removal and application of bioactive material
Other names: Biodentin application
Partial caries removal then application of biodentin
Other names: Biodentin
Time frame: 1year
clinical evaluation: absence of pain , pulp vitality,
………. Radiographic evaluation: absence of any periapical lesion or recurrent caries
Time frame: 1 year
histological evaluation after one year. T (Time): follow up evaluation periods of pulp condition immediately post operative (base line ), after 3, 6, 9 and 12 month and exo-vivo study.
Contact information is provided by the study sponsor or research team.
Abeer M. Shehata, MASTER
CONTACT
Abeer M. Shehata, master
CONTACT
Minia University
Other
Clinical, Radiographical, and Histological Evaluation of Treatment Outcomes Following Different Caries Removal Strategies in Mature Permanent Teeth With Reversible Pulpitis (A Randomized Clinical Trial and Ex-vivo Study)
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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