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NCT Number: NCT07354529

Date Fruit Benefits to Treat Morning Sickness in First Trimester of Pregnancy

The goal of this randomized clinical trial is to evaluate role of date fruit in alleviating morning sickness of pregnancy in pregnant females. The main question[s] it aims to answer [is/are]:

The goal of this randomized clinical trial is to evaluate role of date fruit in

The goal of this randomized clinical trial is to evaluate role of date fruit in alleviating vomiting due to morning sickness of pregnancy and in improving maternal hemoglobin in pregnant females. The main question[s] it aims to answer [are]:

* Role of date fruit in alleviating severity and frequency of vomiting due to morning sickness of pregnancy in pregnant females. * Role of date fruit in improving haemoglobin levels in pregnant females. * To assess improvement of severity and frequency of vomiting due to morning sickness of pregnancy and improvement of hemoglobin levels in pregnant females, researchers will compare date fruit intake with antiemetic medication doxylamine succinate 10 mg + pyridoxine HCl 10 and diet only.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Pregnancy Female Urogenital Diseases and Pregnancy Complications Hyperemesis Gravidarum Morning Sickness Pathological Conditions, Signs and Symptoms Pregnancy Complications Signs and Symptoms Signs and Symptoms, Digestive Urogenital Diseases Vomiting

Age range

18 year–45 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

PNS SHIFA Hospital , Karachi

Karachi, Sindh, Pakistan

About this study

A randomized Controlled trial to assess benefits of date fruit in morning sickness of pregnancy symptoms, inclusive of nausea and vomiting and to improve haemoglobin levels in pregnant females.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Pregnant females in 18 to 45 year old age group

Exclusion criteria

  • Females in 18 to 45 year old age group who are not pregnant.
  • Females less than 18 years old.
  • Females over 45 years.

Treatment and study plan

Date fruit

Other

3 Dates after breakfast

Other names: Date intake in morning

Doxylamine succinate 10 mg + Pyridoxine HCl 10 mg

Drug

Doxylamine succinate 10 mg + Pyridoxine HCl 10 mg , One per day

Other names: Antiemetic once per day

Diet

Other

Avoidance of high in fat foods and enhanced intake of hydrating fruits and vegetables

Other names: Diet as per advice

Primary outcomes

  1. Hemoglobin

    Time frame: 12 Weeks

    Complete blood picture (Laboratory diagnostic tests)

  2. Vomiting

    Time frame: 12 Weeks

    PUQE-24 Score Unabbreviated scale title : The Pregnancy-Unique Quantification of Emesis and Nausea (PUQE-24) Minimum Value : 4-6 (Mild) Maximum Value : ≥13 (Severe) Higher Scores mean worst outcome

Secondary outcomes

  1. Fatigue level

    Time frame: 12 weeks

    FAS Unabbreviated scale title: Fatigue Assessment Scale (FAS)

    Minimum Value : Less less than 22 Maximum Value : 35 or more indicates severe fatigue Higher Scores mean worst outcome

  2. Dietary Recall

    Time frame: 12 weeks

    Direct compliance inquired via telephonic communication on regular basis

Sponsors and collaborators

Lead sponsor

Bahria University

Other

Registry information

Official study title

Evaluation of Benefits of Date Fruit in the First Trimester of Pregnancy

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jan 21, 2026
Registry last updated
Jan 21, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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