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Completed

NCT Number: NCT07513675

Gastric Volume and Fasting Duration in Pregnant Women

This prospective observational study aimed to evaluate the effect of preoperative fasting duration on gastric volume and antral visibility in pregnant women undergoing elective cesarean section. Patients were divided into two groups according to fasting duration (6-8 hours and 8-10 hours), and preoperative gastric ultrasonography was performed to assess antral cross-sectional area and gastric volume.

Additionally, the study investigated the relationship between gastric ultrasound findings and postoperative complications such as nausea and vomiting. The influence of demographic and clinical variables, including age, body mass index, ASA score, and fetal characteristics, on gastric volume was also evaluated.

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Key information

Age range

18 year–45 year

Sex eligibility

Female

Study type

Observational

Primary location

Kartal Dr. Lütfi Kırdar City Hospital

Kartal, Istanbul, 34865, Turkey (Türkiye)

About this study

This prospective observational study was conducted to evaluate the effect of preoperative fasting duration on gastric volume and antral visibility in pregnant women undergoing elective cesarean section. A total of 90 pregnant women were included in the study and divided into two groups based on fasting duration (6-8 hours and 8-10 hours).

Preoperative gastric ultrasonography was performed in all patients to measure antral cross-sectional area and estimate gastric volume. Gastric content was also assessed using antral grading. Demographic and clinical data including age, body mass index, ASA physical status, comorbidities, and fetal characteristics were recorded.

Postoperative outcomes such as nausea, vomiting, and aspiration were evaluated and their relationship with gastric ultrasound findings was analyzed. Additionally, factors affecting gastric volume were assessed using statistical models.

The results of this study may contribute to improved perioperative risk stratification and individualized assessment of aspiration risk in obstetric anesthesia, and may help optimize preoperative fasting protocols.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Pregnant women aged 18-45 years Gestational age between 37-40 weeks Scheduled for elective cesarean section ASA physical status II-III Body mass index (BMI) < 35 kg/m² Undergoing spinal anesthesia

Exclusion criteria

  • BMI ≥ 35 kg/m² Emergency cesarean section Known gastrointestinal disease (e.g., gastroesophageal reflux disease) Use of medications affecting gastric motility History of gastric surgery Presence of infiltrative diseases (e.g., scleroderma, amyloidosis) Use of antiemetic drugs within 24 hours before surgery Severe hypertension during pregnancy (systolic >160 mmHg or diastolic >110 mmHg) Multiple pregnancy Patients who refused to participate

Treatment and study plan

Primary outcomes

  1. Gastric Volume Measured by Ultrasonography

    Time frame: Preoperative period (before anesthesia induction)

    Preoperative gastric volume measured using gastric ultrasonography in pregnant women undergoing elective cesarean section, and comparison between different fasting duration groups (6-8 hours vs 8-10 hours).

Secondary outcomes

  1. Antral Cross-Sectional Area

    Time frame: Preoperative period

    Measurement of gastric antral cross-sectional area using ultrasonography and comparison between fasting duration groups.

Sponsors and collaborators

Lead sponsor

Dr. Lutfi Kirdar Kartal Training and Research Hospital

Other Gov

Registry information

Official study title

Comparison of Gastric Volume Measured by Ultrasonography According to Preoperative Fasting Duration in Pregnant Women Undergoing Elective Cesarean Section and Evaluation of Influencing Factors

Acronym: PREG-GAS

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Apr 7, 2026
Registry last updated
Apr 7, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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