Database of Monochorionic Pregnancies

The purpose of this study is to collect and analyze data regarding natural history, indications for fetal interventions, and maternal and fetal/neonatal outcomes associated with complicated monochorionic twin pregnancy.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Monochorionic Diamniotic Placenta Anemia Anemia, Neonatal Congenital, Hereditary, and Neonatal Diseases and Abnormalities Female Urogenital Diseases and Pregnancy Complications Fetofetal Transfusion Hematologic Diseases Hemic and Lymphatic Diseases Infant, Newborn, Diseases Monochorial Monoamniotic Placenta Pregnancy Complications Twin Reversal Arterial Perfusion Syndrome Twin to Twin Transfusion Syndrome Twin; Complicating Pregnancy Urogenital Diseases

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Miami

Miami, Florida, 33136, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

The study population will consist of MC pregnancies (maternal, fetal, and neonatal data) that have undergone evaluation and/or treatment for complications attributable to monochorionic twin pregnancy at the University of Miami.
Maternal age 18 years and older.

Exclusion criteria

Participation declined or consent not granted in prospective arm
Loss to follow-up

Treatment and study plan

Primary outcomes

Number of participants with Preterm Delivery

Time frame: Up to 42 weeks gestation

Preterm delivery is defined as birth <37 weeks gestation
Number of participant with Premature Spontaneous Rupture of the Membranes

Time frame: Up to 42 weeks

As per clinical evaluation
Number of Infant Deaths

Time frame: Up to 12 months post infant delivery

The Number of Infant Deaths

Sponsors and collaborators

Lead sponsor

University of Miami

Other

Registry information

Official study title

Standardized Prenatal Management and Perinatal Outcome of Complicated Monochorionic Pregnancies

Important dates

Study start: 2022
Primary completion: 2027
Study completion: 2027
First posted: Sep 16, 2022
Registry last updated: May 28, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Not Yet Recruiting