Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders

The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration, and function and to investigate and further characterize the pathophysiology of, clinical manifestations of, and spectrum of disease severity of eosinophilic inflammation in humans.

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Key information

Conditions

Eosinophilic Gastrointestinal Disease Eosinophilic Inflammatory Disease Eosinophilia Food Allergy Food Hypersensitivity Hematologic Diseases Hemic and Lymphatic Diseases Hypersensitivity Hypersensitivity, Immediate Immune System Diseases Leukocyte Disorders

Sex eligibility

All sexes

Study type

Observational

Primary location

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229-3039, United States

Location status: Recruiting

Location contact

Bliss Magella

CONTACT

[email protected]

513-636-7832

Marc E. Rothenberg, M.D., Ph.D.

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Signed informed consent obtained from the patient or parent/guardian. Assent will be obtained from all minors 11 years of age and older.
Carrying a diagnosis of eosinophilic gastrointestinal disease, eosinophilic inflammatory disease, or food allergy OR family member, or normal control

Study contacts

Contact information is provided by the study sponsor or research team.

Bliss Magella

CONTACT

[email protected]

513-636-7832

Sponsors and collaborators

Lead sponsor

Children's Hospital Medical Center, Cincinnati

Other

Registry information

Official study title

Eosinophils and Inflammation, an Expanded Study

Important dates

Study start: 2005
Primary completion: 2050
Study completion: 2050
First posted: Dec 21, 2005
Registry last updated: Sep 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Recruiting