Danish Breast Cancer Group Internal Mammary Node Study

The DBCG IMN study is a nationwide prospective population-based cohort study allocating node-positive breast cancer patients with right-sided tumors to internal mammary node irradiation (IMNI) and patients with left-sided tumors to no IMNI.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Breast Cancer Breast Diseases Breast Neoplasms Neoplasms Neoplasms by Site Skin Diseases Skin and Connective Tissue Diseases

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients with macrometastatic node-positive breast cancer treated with loco-regional radiotherapy.

Exclusion criteria

Prior malignancies, bilateral breast cancer, neoadjuvant systemic therapy, recurrence before radiotherapy, and non-standard radiotherapy.

Treatment and study plan

Internal mammary node irradiation

Radiation

Irradiation of the internal mammary nodes in intercostal space 1-4.

Other names: IMNI

Primary outcomes

Overall survival

Time frame: 15-years.

Censored at end of study or by emigration.

Secondary outcomes

Breast cancer mortality

Time frame: 15-years.

Censored at end of study or by emigration.
Distant recurrences

Time frame: 15-years.

Censored at end of study or by emigration. Death by any cause was regarded as competing event.

Sponsors and collaborators

Lead sponsor

Danish Breast Cancer Cooperative Group

Other

Registry information

Acronym: DBCG IMN

Important dates

Study start: 2003
Primary completion: 2023
Study completion: 2034
First posted: Aug 12, 2024
Registry last updated: Aug 12, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Active, Not Recruiting