Investigation of Medical Management to Prevent Episodes of Diverticulitis Trial
NCT05681559
Digestive System Diseases, Diverticular Diseases
Seattle, Washington, United States
View Trial DetailsNCT Number: NCT03337984
To evaluate the use of damage control surgery by performing bowel resection and laparostomy in the treatment of Hinchey III or IV diverticulitis.
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Observational
Policlinico San Pietro, Ponte San Pietro, Bergamo, Italy
Despite the progress in the resuscitation modalities of septic patients, Hartmann procedure (HP) is still considered the safest treatment for generalized peritonitis as a consequence of a complicated acute diverticulitis (stages III and IV of the Hinchey's classification). Almost the half of those patients do not have their stoma reversed because of its association with significant morbidity and mortality. To date, the use of resection with primary anastomosis (PA) is a matter of debate, as it is reported in the literature that it is substantially equivalent to HP in terms of morbidity and length of postoperative stay. For these reason, PA is often reserved for younger patients with few co-morbidities and a lesser degree of peritoneal contamination. In the last decade, Damage Control Surgery has been emerging as a valid alternative to HP and RA in patients presenting a severe sepsis caused by purulent or fecal peritonitis in acute diverticulitis. Initially described for the treatment of major abdominal injuries, indications for DCS have subsequently been extended to septic shock, abdominal compartment syndrome and impossibility to perform a primary closure. However, there is still no consensus about the use of DCS in perforated acute diverticulitis.
The aim of this study was to describe "how-to-use" the Damage Control Surgery in patients with purulent and fecal peritonitis following a severe acute diverticulitis and report the impact on patients' outcomes after the application of this technique in several Italian centers of emergency surgery
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Inclusion criteria
Exclusion criteria
Time frame: 6 months
Mortality rate related to treatment
Time frame: 6 months
Complications rate arranged by Clavien-Dindo classification I to IV
Time frame: 6 months
Days of stay as inpatient
Time frame: 12 months
Days of stay as
Time frame: 1 month
Observed to expected (O:E) ratio of Hartmann's procedures
University of Roma La Sapienza
Other
Damage Control Surgery in the Treatment of Hinchey Stage III and IV Diverticulitis: an Italian Nationwide Survey
Acronym: DACSCOD
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