Skip to main content
OpenTrials
Completed

NCT Number: NCT03093987

Critical Care Ultrasound Oriented Shock Treatment in ICU

Objective

To investigate whether critical care ultrasound oriented shock management in shock patients in intensive care unit(ICU) can improve outcome.

Methods

Randomized controlled research. Patients were randomly allocated to two groups. In the critical care ultrasound oriented shock management group (CUSS group), treatment was oriented by the findings of critical care ultrasound in each shock phase, while in the control group the decisions about the monitoring and management were made by the clinical team. The goal of treatments in both groups were decreasing lactate by 20% or more per 2 hours for the Optimization phase in shock management, and no increase lactate level when removing the fluid in de-escalation phase. The primary outcome measure were hospital mortality and 28-day mortality, the secondary outcome measure were the length of ventilation and the length of ICU stay.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Shock Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

West China Hospital of Sichuan University

Chengdu, Sichuan, 610041, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • SBP <90 mm Hg or MAP <65 mm Hg or SBP decrease >40mmHg or need vasoactive drugs；
  • Skin that is cold and clammy，capillary refill time >4.5s，urine output of<0.5ml/Kg.hr and lactate >2mmol/L；
  • SHOCK presented within 6 hr.

Exclusion criteria

  • <18 years old；
  • Pregnancy；
  • Patient or family member refuse to be enrolled.

Treatment and study plan

Critical Care Ultrasound

Other

Circulateory will be managed according to the result of critical ultrasound joint clearance of lactic acid in patients with shock

Primary outcomes

  1. 28-day mortality

    Time frame: through study completion,an average of 28 days

    28-day mortality

Secondary outcomes

  1. the length of ICU stay

    Time frame: through study completion,an average of 28 days

    the length of ICU stay

  2. the total length of hospital stay

    Time frame: through study completion,an average of 28 days

    the total length of hospital stay

  3. the incidence of AKI

    Time frame: through study completion,an average of 28 days

    the incidence of AKI

Sponsors and collaborators

Lead sponsor

West China Hospital

Other

Registry information

Important dates

Study start
2017
Primary completion
2017
Study completion
2017
First posted
Mar 28, 2017
Registry last updated
Nov 1, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.